Tick salivary kunitz-type inhibitors: targeting host hemostasis and immunity to mediate successful blood feeding
Kunitz domain-containing proteins are ubiquitous serine protease inhibitors with promising
therapeutic potential. They target key proteases involved in major cellular processes such as …
therapeutic potential. They target key proteases involved in major cellular processes such as …
Proteome-Wide Multicenter Mendelian Randomization Analysis to Identify Novel Therapeutic Targets for Lung Cancer
K Wang, H Yi, Y Wang, D Jin, G Zhang… - Archivos de …, 2024 - Elsevier
Introduction Lung cancer (LC) remains a leading cause of cancer mortality worldwide,
underscoring the urgent need for novel therapeutic targets. The integration of Mendelian …
underscoring the urgent need for novel therapeutic targets. The integration of Mendelian …
Structural and functional properties of the Kunitz-type and C-terminal domains of Amblyomin-X supporting its antitumor activity
Amblyomin-X is a Kunitz-type FXa inhibitor identified through the transcriptome analysis of
the salivary gland from Amblyomma sculptum tick. This protein consists of two domains of …
the salivary gland from Amblyomma sculptum tick. This protein consists of two domains of …