Advanced diagnostic technologies, such as polymerase chain reaction (PCR) and enzyme-
linked immunosorbent assay (ELISA), have been widely used in well-equipped laboratories …

Sickle cell disease (SCD) is a widespread disease caused by a mutation in the beta-globin
gene that leads to the production of abnormal hemoglobin called hemoglobin S. The …

Sickle cell disease is a common and life-threatening haematological disorder that affects
millions of people worldwide. Abnormal sickle-shaped erythrocytes disrupt blood flow in …

Blood is the most intensely studied human biofluid and is used as the main indicator of the
health status of an individual. Blood is a very complex fluid, containing a multiplicity of …

This review shows the recent advances and state of the art in paper-based analytical
devices (PADs) through the analysis of their integration with microfluidics and LOC micro …

Sickle cell disease (SCD) is a major public health priority throughout much of the world,
affecting millions of people. In many regions, particularly those in resource-limited settings …

Sickle cell disease affects 25% of people living in Central and West Africa and, if left
undiagnosed, can cause life threatening “silent” strokes and lifelong damage. However …

Although effective low-cost interventions exist, child mortality attributable to sickle cell
disease (SCD) remains high in low-resource areas due, in large part, to the lack of …

Background Sickle cell disease is one of the most common inherited blood disorders.
Universal screening and early intervention have significantly helped to reduce childhood …

The quantification of blood cells provides critical information about a patient's health status.
Sophisticated analytical equipment, such as hematology analyzers, have been developed to …