Life History and Developmental Processes in the Basidiomycete Coprinus cinereus

U Kües - Microbiology and molecular biology reviews, 2000 - Am Soc Microbiol
Coprinus cinereus has two main types of mycelia, the asexual monokaryon and the sexual
dikaryon, formed by fusion of compatible monokaryons. Syngamy (plasmogamy) and …

Mechanism and control of meiotic recombination initiation

S Keeney - 2001 - Elsevier
Homologous recombination is essential during meiosis in most sexually reproducing
organisms. In budding yeast, and most likely in other organisms as well, meiotic …

Chromosome synapsis defects and sexually dimorphic meiotic progression in mice lacking Spo11

F Baudat, K Manova, JP Yuen, M Jasin, S Keeney - Molecular cell, 2000 - cell.com
Spo11, a protein first identified in yeast, is thought to generate the chromosome breaks that
initiate meiotic recombination. We now report that disruption of mouse Spo11 leads to …

Spo11 and the formation of DNA double-strand breaks in meiosis

S Keeney - Recombination and meiosis: crossing-over and …, 2007 - Springer
Meiotic recombination is carried out through a specialized pathway for the formation and
repair of DNA double-strand breaks made by the Spo11 protein, a relative of archaeal …

Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice

R Kumar, HM Bourbon, B De Massy - Genes & development, 2010 - genesdev.cshlp.org
Meiotic recombination is initiated by the programmed induction of DNA double-strand
breaks (DSBs) catalyzed by the evolutionarily conserved Spo11 protein. Studies in yeast …

[PDF][PDF] Initiation of meiotic recombination by formation of DNA double-strand breaks: mechanism and regulation

S Keeney, MJ Neale - Biochemical Society Transactions, 2006 - researchgate.net
Homologous recombination is essential for accurate chromosome segregation during
meiosis in most sexual organisms. Meiotic recombination is initiated by the formation of …

A High Throughput Genetic Screen Identifies New Early Meiotic Recombination Functions in Arabidopsis thaliana

A De Muyt, L Pereira, D Vezon, L Chelysheva… - PLoS …, 2009 - journals.plos.org
Meiotic recombination is initiated by the formation of numerous DNA double-strand breaks
(DSBs) catalysed by the widely conserved Spo11 protein. In Saccharomyces cerevisiae …

Mre11 deficiency in Arabidopsis is associated with chromosomal instability in somatic cells and Spo11-dependent genome fragmentation during meiosis

J Puizina, J Siroky, P Mokros, D Schweizer… - The Plant …, 2004 - academic.oup.com
Abstract The Mre11/Rad50/Nbs1 complex is involved in many aspects of chromosome
metabolism. Aberrant function of the complex is associated with defects in the DNA …

Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism

C Arora, K Kee, S Maleki, S Keeney - Molecular cell, 2004 - cell.com
Meiotic recombination initiates with double-strand breaks (DSBs) catalyzed by Spo11 in
conjunction with accessory proteins whose roles are not understood. Two-hybrid analysis …

Lessons learned from BRCA1 and BRCA2

L Zheng, S Li, TG Boyer, WH Lee - Oncogene, 2000 - nature.com
BRCA1 and BRCA2 are breast cancer susceptibility genes. Mutations within BRCA1 and
BRCA1 are responsible for most familial breast cancer cases. Targeted deletion of Brca1 or …