Triazoles and their derivatives: Chemistry, synthesis, and therapeutic applications

MM Matin, P Matin, MR Rahman… - Frontiers in molecular …, 2022 - frontiersin.org
Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior
pharmacological applications. Structurally, there are two types of five-membered triazoles: 1 …

Triazole hybrid compounds: A new frontier in malaria treatment

L Ravindar, SA Hasbullah, KP Rakesh… - European Journal of …, 2023 - Elsevier
Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …

Benzimidazole-triazole hybrids as antimicrobial and antiviral agents: A systematic review

M Marinescu - Antibiotics, 2023 - mdpi.com
Bacterial infections have attracted the attention of researchers in recent decades, especially
due to the special problems they have faced, such as their increasing diversity and …

Synthesis, reactions and application of chalcones: A systematic review

MA Shalaby, SA Rizk, AM Fahim - Organic & Biomolecular Chemistry, 2023 - pubs.rsc.org
Chalcones are a group of naturally occurring compounds that have biological effects that
include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone …

Emerging impact of triazoles as anti-tubercular agent

A Sharma, AK Agrahari, S Rajkhowa… - European Journal of …, 2022 - Elsevier
Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

Ionic Liquids for Green Synthesis of 1, 2, 3-Triazoles: A systematic Review

A Kumar, V Kumar, P Singh, RK Tittal, K Lal - Green Chemistry, 2024 - pubs.rsc.org
The exponentially increasing use of hazardous traditional organic solvents and catalysts for
more accessible synthesis of important heterocycles useful for humankind in various fields …

The antibacterial activity of 1, 2, 3-triazole-and 1, 2, 4-triazole-containing hybrids against Staphylococcus aureus: An updated review (2020-present)

J Li, J Zhang - Current Topics in Medicinal Chemistry, 2022 - ingentaconnect.com
Staphylococcus aureus (S. aureus), a prominent, highly contagious nosocomial and
community-acquired bacterial pathogen, can cause a broad spectrum of diseases. Antibiotic …

A review on the synthesis and pharmacological activity of heterocyclic compounds

J Baranwal, S Kushwaha, S Singh… - Current Physical …, 2023 - ingentaconnect.com
Biologically active compounds play a very important role in our daily life. Almost all
biologically active compounds contain heteroatoms and among these, a major portion is …

Bio-oriented synthesis and molecular docking studies of 1, 2, 4-triazole based derivatives as potential anti-cancer agents against HepG2 cell line

N Akhter, S Batool, SG Khan, N Rasool, F Anjum… - Pharmaceuticals, 2023 - mdpi.com
Triazole-based acetamides serve as important scaffolds for various pharmacologically active
drugs. In the present work, structural hybrids of 1, 2, 4-triazole and acetamides were …

Exploring Triazole-Based Drugs: Synthesis, Application, FDA Approvals, and Clinical Trial Updates-A Comprehensive Review

J Khan, A Rani, M Aslam, RS Maharia, G Pandey… - Tetrahedron, 2024 - Elsevier
Triazole-based drugs are a dynamic class of compounds exhibiting extensive therapeutic
potential. This comprehensive review explores the synthesis, application, FDA approvals …