Cardiometabolic risk factors associated with type 2 diabetes mellitus: a mechanistic insight

S Chakraborty, A Verma, R Garg… - Clinical Medicine …, 2023 - journals.sagepub.com
A complex metabolic condition referred to as Type 2 diabetes mellitus (T2DM) is
characterized by insulin resistance (IR) and decreased insulin production. Obesity …

[HTML][HTML] The role of epicardial adipose tissue dysfunction in cardiovascular diseases: An overview of pathophysiology, evaluation, and management

C Li, X Liu, BK Adhikari, L Chen, W Liu… - Frontiers in …, 2023 - frontiersin.org
In recent decades, the epicardial adipose tissue (EAT) has been at the forefront of scientific
research because of its diverse role in the pathogenesis of cardiovascular diseases (CVDs) …

Body fat distribution, diabetes mellitus, and cardiovascular disease: an update

PS Kang, IJ Neeland - Current Cardiology Reports, 2023 - Springer
Abstract Purpose of Review Specific measures of body fat distribution may have particular
value in the development and treatment of cardiometabolic conditions, such as …

[HTML][HTML] Atrial fibrillation and chronic coronary ischemia: A challenging vicious circle

AF Oancea, RA Jigoranu, PC Morariu, RS Miftode… - Life, 2023 - mdpi.com
Atrial fibrillation, the most frequent arrhythmia in clinical practice and chronic coronary
syndrome, is one of the forms of coronary ischemia to have a strong dual relationship. Atrial …

Should atrial fibrillation be considered a vascular disease? The need for a comprehensive vascular approach

C Escobar-Cervantes, AP Reino… - Expert Review of …, 2023 - Taylor & Francis
Introduction Atrial fibrillation (AF) cannot be considered an isolated disease. Patients with AF
should be managed using a comprehensive approach that is not limited to stroke …

[HTML][HTML] Role of Epicardial Adipose Tissue Secretome on Cardiovascular Diseases

S Leo, E Tremoli, L Ferroni, B Zavan - Biomedicines, 2023 - mdpi.com
Obesity and insulin resistance are associated with the inflamed and defective adipose tissue
(AT) phenotype, and are established risk factors for cardiovascular diseases (CVDs) …

[HTML][HTML] Increased circulating progranulin is not sufficient to induce cardiac dysfunction or supraventricular arrhythmia

KE McElhanon, TC Huff, D Hirenallur-Shanthappa… - Scientific Reports, 2023 - nature.com
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, and the incidence of new-
onset AF has been increasing over the past two decades. Several factors contribute to the …

[HTML][HTML] Single-nucleus transcriptomics of epicardial adipose tissue from female pigs reveals effects of exercise training on resident innate and adaptive immune cells

I Ahmad, S Gupta, P Faulkner, D Mullens… - Cell Communication and …, 2024 - Springer
Background Coronary artery disease (CAD) is a leading cause of death in women.
Epicardial adipose tissue (EAT) secretes cytokines to modulate coronary artery function, and …

[HTML][HTML] Epicardial Adipose Tissue Thickness and Preserved Ejection Fraction Heart Failure

A Dhore-Patil, D Urina-Jassir, R Samson… - Current Hypertension …, 2024 - Springer
Abstract Purpose of the Review Preserved ejection fraction heart failure and obesity
frequently coexist. Whether obesity plays a consistent role in the pathogenesis of preserved …

Adipocyte-mediated electrophysiological remodeling of human stem cell-derived cardiomyocytes

J Morrissette-McAlmon, WR Xu, R Teuben… - Journal of Molecular and …, 2024 - Elsevier
Adipocytes normally accumulate in the epicardial and pericardial layers around the human
heart, but their infiltration into the myocardium can be proarrhythmic. Methods and results …