Inflammatory Bowel Disease (IBD) is characterized by a loss of intestinal barrier function
caused by an aberrant interaction between the immune response and the gut microbiota. In …

Background The immune system, composed of organs, tissues, cells, and proteins, is the
key to protecting the body from external biological attacks and inflammation. The latter …

ROS in cancer cells play a key role in pathways regulating cell death, stemness
maintenance, and metabolic reprogramming, all of which have been implicated in resistance …

Osteoarthritis (OA) is an inflammation-driven degenerative joint disease. Human salivary
peptide histatin-1 (Hst1) shows pro-healing and immunomodulatory properties. but its role in …

Heavy metal exposure leads to multiple system dysfunctions. The mechanisms are likely
multifactorial and involve inflammation and oxidative stress. The aim of this study was to …

Non-alcoholic fatty liver disease (NAFLD) is a liver disorder characterized by fat
accumulation in at least 5% of the liver cells in individuals without significant alcohol …

Genome-wide association studies in inflammatory bowel disease have identified risk loci in
the orosomucoid-like protein 3/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) …