The role of cholesterol and mitochondrial bioenergetics in activation of the inflammasome in IBD
J Astorga, N Gasaly, K Dubois-Camacho… - Frontiers in …, 2022 - frontiersin.org
Inflammatory Bowel Disease (IBD) is characterized by a loss of intestinal barrier function
caused by an aberrant interaction between the immune response and the gut microbiota. In …
caused by an aberrant interaction between the immune response and the gut microbiota. In …
A bibliometric analysis: Ca2+ fluxes and inflammatory phenotyping by flow cytometry in peripheral blood mononuclear cells
C Brun, L Chalet, F Moulin, T Bochaton… - Frontiers in …, 2023 - frontiersin.org
Background The immune system, composed of organs, tissues, cells, and proteins, is the
key to protecting the body from external biological attacks and inflammation. The latter …
key to protecting the body from external biological attacks and inflammation. The latter …
Targeting M2 macrophages with a novel NADPH oxidase inhibitor
ROS in cancer cells play a key role in pathways regulating cell death, stemness
maintenance, and metabolic reprogramming, all of which have been implicated in resistance …
maintenance, and metabolic reprogramming, all of which have been implicated in resistance …
Human salivary histatin-1 attenuates osteoarthritis through promoting M1/M2 macrophage transition
A Wu, JL Pathak, X Li, W Cao, W Zhong, M Zhu, Q Wu… - Pharmaceutics, 2023 - mdpi.com
Osteoarthritis (OA) is an inflammation-driven degenerative joint disease. Human salivary
peptide histatin-1 (Hst1) shows pro-healing and immunomodulatory properties. but its role in …
peptide histatin-1 (Hst1) shows pro-healing and immunomodulatory properties. but its role in …
[HTML][HTML] In vivo chronic exposure to inorganic mercury worsens hypercholesterolemia, oxidative stress and atherosclerosis in the LDL receptor knockout mice
MIC Queiroz, CM Lazaro, LMB Dos Santos… - Ecotoxicology and …, 2024 - Elsevier
Heavy metal exposure leads to multiple system dysfunctions. The mechanisms are likely
multifactorial and involve inflammation and oxidative stress. The aim of this study was to …
multifactorial and involve inflammation and oxidative stress. The aim of this study was to …
OPEN ACCESS EDITED BY
RJ Brummer, H Li, A Alisi, CJ Beltrán… - … Metabolites and Host …, 2024 - books.google.com
Non-alcoholic fatty liver disease (NAFLD) is a liver disorder characterized by fat
accumulation in at least 5% of the liver cells in individuals without significant alcohol …
accumulation in at least 5% of the liver cells in individuals without significant alcohol …
ORMDL3 regulates NLRP3 inflammasome activation by maintaining ER-mitochondria contacts in human macrophages and dictates ulcerative colitis patient outcome
J Sharma, S Khan, NC Singh, S Sahu, D Raj… - Journal of Biological …, 2024 - ASBMB
Genome-wide association studies in inflammatory bowel disease have identified risk loci in
the orosomucoid-like protein 3/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) …
the orosomucoid-like protein 3/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) …