Effect of saffron, black seed, and their main constituents on inflammatory cytokine response (mainly TNF-α) and oxidative stress status: An aspect on pharmacological …

Z Vafaeipour, M Ghasemzadeh Rahbardar… - Naunyn-Schmiedeberg's …, 2023 - Springer
Tumor necrosis factor-α (TNF-α), an inflammatory cytokine, is produced by monocytes and
macrophages. It is known as a'double-edged sword'because it is responsible for …

EGCG alleviated Mn exposure-caused carp kidney damage via trpm2-NLRP3-TNF-α-JNK pathway: Oxidative stress, inflammation, and tight junction dysfunction

Q Zhou, J Cui, Y Liu, L Gu, X Teng, Y Tang - Fish & shellfish immunology, 2023 - Elsevier
Manganese (Mn), an essential trace metal element in organisms. However, with extensive
use of Mn in industry and agriculture, Mn becomes a heavy metal pollutant in water.(−) …

[HTML][HTML] Hepato-and reno-protective effects of thymoquinone, crocin, and carvacrol: A comprehensive review

A Anaeigoudari - Asian Pacific Journal of Tropical Biomedicine, 2022 - journals.lww.com
Medicinal plants are rich in nutrients and phytochemicals which prevent and treat a wide
range of ailments. Accumulating experimental studies exhibit that some bioactive …

Analysis of relationship between mixed heavy metal exposure and early renal damage based on a weighted quantile sum regression and Bayesian kernel machine …

Q An, Q Wang, R Liu, J Zhang, S Li, W Shen… - Journal of Trace …, 2024 - Elsevier
Background Occupation, environmental heavy metal exposure, and renal function
impairment are closely related. The relationship between mixed metal exposure and chronic …

Utilization of Nanotechnology to Improve Bone Health in Osteoporosis Exploiting Nigella sativa and Its Active Constituent Thymoquinone

J Ahmad, HA Albarqi, MZ Ahmad, MAA Orabi, S Md… - Bioengineering, 2022 - mdpi.com
Osteoporosis, a chronic bone disorder, is one of the leading causes of fracture and morbidity
risk. Numerous medicinally important herbs have been evaluated for their efficacy in …

Thymoquinone: An Effective Natural Compound for Kidney Protection

H Zhang, Y Liu, Y Dong, G Li, S Wang - The American Journal of …, 2024 - World Scientific
Kidney disease is a common health problem worldwide. Acute or chronic injuries may
interfere with kidney functions, eventually resulting in irreversible kidney damage. A number …

[HTML][HTML] Antidepressant and anti-nociceptive effects of Nigella sativa and its main constituent, thymoquinone: A literature review

A Anaeigoudari - Asian Pacific Journal of Tropical Biomedicine, 2022 - journals.lww.com
Medicinal plants and their ingredients have beneficial effects on human health. Nigella
sativa is a herbal plant with multiple biological and pharmacological activities. Previous …

Vildagliptin Treatment Ameliorates Renal Interstitial Fibrosis in a Murine Model of Unilateral Ureteral Obstruction

S Honma, S Kakuage, Y Morita, T Ito… - Biological and …, 2024 - jstage.jst.go.jp
Renal interstitial fibrosis in mice can be modeled using unilateral ureteral obstruction (UUO).
Here, we investigated the anti-fibrotic effects of the dipeptidyl peptidase-4 inhibitor …

[PDF][PDF] Toxicity assessment due to chronic exposure to manganese in male Wistar rat

H Harifi, M Lamtai, SA Salhi, FZ Azzaoui… - Adv. Anim. Vet …, 2024 - researchgate.net
Manganese (Mn) is present everywhere: in rocks, soil, water, food, and in various forms. Our
bodies utilize it to contribute to energy metabolism and perform many other functions, but …

Protective role of thymoquinone against acrylamide-induced nephrotoxicity in rats

AM Ghonim - Benha Veterinary Medical Journal, 2023 - journals.ekb.eg
The goal of this study was to see how thymoquinone (TQ) altered acrylamide (ACR) induced
toxicity in rats. The current study was carried out on 28 male Wistar rats divided into 4 …