Chemotherapy resistance: Role of mitochondrial and autophagic components
E Bahar, SY Han, JY Kim, H Yoon - Cancers, 2022 - mdpi.com
Simple Summary Chemotherapy resistance is a common occurrence during cancer
treatment that cancer researchers are attempting to understand and overcome. Mitochondria …
treatment that cancer researchers are attempting to understand and overcome. Mitochondria …
Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response
M Ashrafizadeh, MDA Paskeh, S Mirzaei… - Journal of Experimental …, 2022 - Springer
Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …
Multiplexed organelles portrait barcodes for subcellular microRNA array detection in living cells
W Wei, H Lu, W Dai, X Zheng, H Dong - ACS nano, 2022 - ACS Publications
Multiplexed profiling of microRNAs' subcellular expression and distribution is essential to
understand their spatiotemporal function information, but it remains a crucial challenge …
understand their spatiotemporal function information, but it remains a crucial challenge …
Modulating Nitric Oxide: Implications for Cytotoxicity and Cytoprotection
Despite the significant progress in the fields of biology, physiology, molecular medicine, and
pharmacology; the designation of the properties of nitrogen monoxide in the regulation of life …
pharmacology; the designation of the properties of nitrogen monoxide in the regulation of life …
Mipsagargin: The beginning—Not the end—Of thapsigargin prodrug-based cancer therapeutics
Søren Brøgger Christensen isolated and characterized the cell-penetrant sesquiterpene
lactone Thapsigargin (TG) from the fruit Thapsia garganica. In the late 1980s/early 1990s …
lactone Thapsigargin (TG) from the fruit Thapsia garganica. In the late 1980s/early 1990s …
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as a Sensor of Oxidative Stress in Cancer Cells
F Moccia, D Montagna - Cells, 2023 - mdpi.com
Moderate levels of reactive oxygen species (ROS), such as hydrogen peroxide (H2O2), fuel
tumor metastasis and invasion in a variety of cancer types. Conversely, excessive ROS …
tumor metastasis and invasion in a variety of cancer types. Conversely, excessive ROS …
Mitochondrial signaling pathways and their role in cancer drug resistance
Mitochondria, traditionally known as cellular powerhouses, now emerge as critical signaling
centers influencing cancer progression and drug resistance. The review highlights the role …
centers influencing cancer progression and drug resistance. The review highlights the role …
Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technology
Y Zhang, W Lv, H Li, T Dong, H Wu, C Su, H Shu… - Cancer Cell …, 2022 - Springer
Background Ultrasound-targeted microbubble destruction (UTMD) technology is a new drug
and gene delivery strategy. This study investigates novel ultrasound (US) sensitive siRNA …
and gene delivery strategy. This study investigates novel ultrasound (US) sensitive siRNA …
Amplifying Ca2+ Overload by Engineered Biomaterials for Synergistic Cancer Therapy
JL Liang, Y Cao, K Lv, B Xiao, J Sun - Biomaterials, 2024 - Elsevier
Ca 2+ overload is one of the most widely causes of inducing apoptosis, pyroptosis,
immunogenic cell death, autophagy, paraptosis, necroptosis, and calcification of tumor cells …
immunogenic cell death, autophagy, paraptosis, necroptosis, and calcification of tumor cells …
[HTML][HTML] The mechanisms of Ca2+ regulating autophagy and its research progress in neurodegenerative diseases: A review
M Hou, Z Zhang, Z Fan, L Huang, L Wang - Medicine, 2024 - journals.lww.com
Neurodegenerative diseases are complex disorders that significantly challenge human
health, with their incidence increasing with age. A key pathological feature of these diseases …
health, with their incidence increasing with age. A key pathological feature of these diseases …