Since its discovery, the CRISPR/Cas technology has rapidly become an essential tool in
modern biomedical research. The opportunities to specifically modify and correct genomic …

CRISPR‐based genome editing technology has become an important potential therapeutic
tool for various diseases. A vital challenge is to reach a safe, efficient, and clinically suitable …

Messenger RNA is a class of promising nucleic acid therapeutics to treat a variety of
diseases, including genetic diseases. The development of a stable and efficacious mRNA …

Gene therapy is a promising strategy for treating challenging diseases. The successful
delivery of genes is a critical step for gene therapy. However, concerns about …

The cellular transport process of DNA is hampered by cell membrane barriers, and hence, a
delivery vehicle is essential for realizing the potential benefits of gene therapy to combat a …

Rapid detection of nucleic acids (DNA or RNA) by inexpensive, selective, accurate, and
highly sensitive methods is very important for biosensors. DNA-sensors based on DNA …

With the development of genome editing techniques, gene therapy is becoming a viable
option for the treatment of a variety of human diseases. Genome editing techniques mainly …

Transmucosal administration offers numerous advantages for drug delivery as it usually
helps to avoid first pass metabolism, provides rapid onset of action, and is a non-invasive …

Inhaled drug delivery has been an emerging route for the treatment of lung diseases with
clear advantages over oral and intravenous routes. However, the delivery efficacy is affected …

Liposomes are one of the most widely investigated carriers for CRISPR/Cas9 delivery. The
surface properties of liposomal carriers, including the surface charge, PEGylation, and …