High-throughput techniques based on restriction site-associated DNA sequencing (RADseq)
are enabling the low-cost discovery and genotyping of thousands of genetic markers for any …

If we restrict the use of Homo sapiens in the fossil record to specimens which share a
significant number of derived features in the skeleton with extant H. sapiens, the origin of our …

Denisovans are members of a hominin group who are currently only known directly from
fragmentary fossils, the genomes of which have been studied from a single site, Denisova …

To date, the only Neandertal genome that has been sequenced to high quality is from an
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …

Due to postmortem DNA degradation and microbial colonization, most ancient genomes
have low depth of coverage, hindering genotype calling. Genotype imputation can improve …

Modern humans have large and globular brains that distinguish them from their extinct
Homo relatives. The characteristic globularity develops during a prenatal and early postnatal …

Although a rich record of Pleistocene human-associated archaeological assemblages
exists, the scarcity of hominin fossils often impedes the understanding of which hominins …

It has been shown that Neanderthals contributed genetically to modern humans outside
Africa 47,000–65,000 years ago. Here we analyse the genomes of a Neanderthal and a …

As modern and ancient DNA sequence data from diverse human populations accumulate,
evidence is increasing in support of the existence of beneficial variants acquired from …

Abstract Approximately 2–4% of genetic material in human populations outside Africa is
derived from Neanderthals who interbred with anatomically modern humans. Recent studies …