A journey into the world of insect lipid metabolism

U Toprak, D Hegedus, C Doğan… - Archives of insect …, 2020 - Wiley Online Library
Lipid metabolism is fundamental to life. In insects, it is critical, during reproduction, flight,
starvation, and diapause. The coordination center for insect lipid metabolism is the fat body …

Triacylglycerol Metabolism in Drosophila melanogaster

C Heier, RP Kühnlein - Genetics, 2018 - academic.oup.com
Triacylglycerol (TAG) is the most important caloric source with respect to energy
homeostasis in animals. In addition to its evolutionarily conserved importance as an energy …

Molecular basis of juvenile hormone signaling

M Jindra, X Bellés, T Shinoda - Current Opinion in Insect Science, 2015 - Elsevier
Highlights•bHLH-PAS proteins Met and Tai form a JH receptor that mediates JH function in
vivo.•The Met–Tai receptor complex is a JH-activated transcription factor.•JH activates Met …

Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African Trypanosomiasis

International Glossina Genome Initiative, GM Attardo… - Science, 2014 - science.org
Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan
Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease …

[HTML][HTML] The role of peptide hormones in insect lipid metabolism

U Toprak - Frontiers in Physiology, 2020 - frontiersin.org
Lipids are the primary storage molecules and an essential source of energy in insects during
reproduction, prolonged periods of flight, starvation, and diapause. The coordination center …

[HTML][HTML] Eat to reproduce: a key role for the insulin signaling pathway in adult insects

L Badisco, P Van Wielendaele… - Frontiers in …, 2013 - frontiersin.org
Insects, like all heterotrophic organisms, acquire from their food the nutrients that are
essential for anabolic processes that lead to growth (larval stages) or reproduction (adult …

Krüppel-homolog 1 mediates juvenile hormone action to promote vitellogenesis and oocyte maturation in the migratory locust

J Song, Z Wu, Z Wang, S Deng, S Zhou - Insect biochemistry and molecular …, 2014 - Elsevier
Juvenile hormone (JH) prevents insect larval metamorphosis and stimulates processes for
adult reproduction. Krüppel-homolog 1 (Kr-h1), a zinc finger transcription factor, is shown to …

Vitamin B6 Generated by Obligate Symbionts Is Critical for Maintaining Proline Homeostasis and Fecundity in Tsetse Flies

V Michalkova, JB Benoit, BL Weiss… - Applied and …, 2014 - Am Soc Microbiol
The viviparous tsetse fly utilizes proline as a hemolymph-borne energy source. In tsetse,
biosynthesis of proline from alanine involves the enzyme alanine-glyoxylate …

[HTML][HTML] Juvenile hormone suppresses resistance to infection in mated female Drosophila melanogaster

RA Schwenke, BP Lazzaro - Current Biology, 2017 - cell.com
Hormonal signaling provides metazoans with the ability to regulate development, growth,
metabolism, immune defense, and reproduction in response to internal and external stimuli …

Lipid metabolism in insect disease vectors

KC Gondim, GC Atella, EG Pontes… - Insect biochemistry and …, 2018 - Elsevier
More than a third of the world population is at constant risk of contracting some insect-
transmitted disease, such as Dengue fever, Zika virus disease, malaria, Chagas' disease …