[HTML][HTML] Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes

A McGuigan, P Kelly, RC Turkington… - World journal of …, 2018 - ncbi.nlm.nih.gov
This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma
risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further …

From somatic mutation to early detection: insights from molecular characterization of pancreatic cancer precursor lesions

CG Fischer, LD Wood - The Journal of pathology, 2018 - Wiley Online Library
Pancreatic cancer arises from noninvasive precursor lesions, including pancreatic
intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and …

MIA PaCa-2 and PANC-1–pancreas ductal adenocarcinoma cell lines with neuroendocrine differentiation and somatostatin receptors

R Gradiz, HC Silva, L Carvalho, MF Botelho… - Scientific reports, 2016 - nature.com
Studies using cell lines should always characterize these cells to ensure that the results are
not distorted by unexpected morphological or genetic changes possibly due to culture time …

An aggrephagy-related LncRNA signature for the prognosis of pancreatic adenocarcinoma

X Huang, H Chi, S Gou, X Guo, L Li, G Peng, J Zhang… - Genes, 2023 - mdpi.com
Pancreatic adenocarcinoma (PAAD) is a common, highly malignant, and aggressive
gastrointestinal tumor. The conventional treatment of PAAD shows poor results, and patients …

Impact of next-generation sequencing on the clinical diagnosis of pancreatic cysts

M Jones, Z Zheng, J Wang, J Dudley… - Gastrointestinal …, 2016 - Elsevier
Background and Aims The value of next-generation sequencing (NGS) of pancreatic cyst
fluid relative to the clinical and imaging impression has not been well-studied. The aim of …

Next‐generation sequencing adds value to the preoperative diagnosis of pancreatic cysts

MW Rosenbaum, M Jones, JC Dudley… - Cancer …, 2017 - Wiley Online Library
BACKGROUND The diagnosis of a pancreatic cyst as mucinous or high‐risk dictates the
need for follow‐up or surgery. Molecular analysis of aspirated pancreatic cyst fluid (PCF) …

KRAS, GNAS, and RNF43 mutations in intraductal papillary mucinous neoplasm of the pancreas: a meta-analysis

JH Lee, Y Kim, JW Choi, YS Kim - Springerplus, 2016 - Springer
Background The prevalence and clinical significances of KRAS, GNAS, and RNF43
mutations in patients with pancreatic intraductal papillary mucinous neoplasm (IPMN) …

Intraductal neoplasms of the pancreas

G Klöppel, O Basturk, AM Schlitter… - Seminars in diagnostic …, 2014 - Elsevier
There are three types of pancreatic neoplasms that predominantly have an intraductal
growth pattern: the common, usually cystic, intraductal papillary mucinous neoplasms …

Precursor lesions of pancreatic cancer

JY Kim, SM Hong - Oncology research and treatment, 2018 - karger.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer death.
Although the treatment modalities are improving, the prognosis of PDAC continues to be …

Morphological heterogeneity in ductal adenocarcinoma of the pancreas–Does it matter?

C Verbeke - Pancreatology, 2016 - Elsevier
Morphological heterogeneity is a common finding in pancreatic ductal adenocarcinoma.
Inter-and intra-tumour heterogeneity relates not only to the microscopic appearances of the …