Tryptophan (Trp) metabolism primarily involves the kynurenine, 5-hydroxytryptamine, and
indole pathways. A variety of bioactive compounds produced via Trp metabolism can …

Positron emission tomography (PET) is an imaging technology that can detect and
characterize tumors based on their molecular and biochemical properties, such as altered …

The kynurenine pathway is a major route of l-tryptophan catabolism producing neuroactive
metabolites implicated in neurodegeneration and immune tolerance. We characterized the …

The kynurenine pathway (KP) is the principal route of L-tryptophan (TRP) catabolism leading
to the production of kynurenine (KYN), the neuroprotectants, kynurenic acid (KYNA) and …

Since prediction of long-term seizure outcome using preoperative diagnostic modalities
remains suboptimal in epilepsy surgery, we evaluated whether interictal spike frequency …

Early diagnosis is essential for completely eradicating skin cancer and maximizing patients'
clinical benefits. Emerging optical imaging modalities such as reflectance confocal …

Brain tumors are among the most common and most chemoresistant tumors. Despite
treatment with aggressive treatment strategies, the prognosis for patients harboring …

Raman diagnostics and imaging have been shown to be an effective tool for the analysis
and discrimination of human brain tumors from normal structures. Raman spectroscopic …

Simple Summary After leukemias, brain tumors are the most common cancers in children,
and early, accurate diagnosis is critical to improve patient outcomes. Beyond the …

18F-fluorodeoxyglucose positron emission tomography (FDG-PET) and FDG-PET/computed
tomography (CT) are becoming increasingly important imaging tools in the noninvasive …