Visualizing and perturbing neural activity on a brain-wide scale in model animals and
humans is a major goal of neuroscience technology development. Established electrical and …

The mammalian immune system has evolved in the presence of a complex community of
indigenous microorganisms that constitutively colonize all barrier surfaces. This intimate …

The ability to physically manipulate specific cells is critical for the fields of biomedicine,
synthetic biology, and living materials. Ultrasound has the ability to manipulate cells with …

Ultrasound allows imaging at a much greater depth than optical methods, but existing
genetically encoded acoustic reporters for in vivo cellular imaging have been limited by poor …

The study of cellular processes occurring inside intact organisms requires methods to
visualize cellular functions such as gene expression in deep tissues. Ultrasound is a widely …

Visualizing biomolecular and cellular processes inside intact living organisms is a major
goal of chemical biology. However, existing molecular biosensors, based primarily on …

Acoustic reporter genes (ARGs) that encode air-filled gas vesicles enable ultrasound-based
imaging of gene expression in genetically modified bacteria and mammalian cells …

Tumor hypoxia is believed to be a factor limiting successful outcomes of oxygen-consuming
cancer therapy, thereby reducing patient survival. A key strategy to overcome tumor hypoxia …

Microorganisms have gained defense systems during the lengthy process of evolution over
millions of years. Such defense systems can protect them from being attacked by invading …

Sonodynamic therapy (SDT) is a promising alternative for cancer therapy, understood to
exert cytotoxicity through cavitation and subsequent production of large amounts of reactive …