Breast cancer is often a fatal disease that has a substantial impact on the female mortality
rate. Rapidly spreading breast cancer is due to the abnormal growth of malignant cells in the …

Since four decades mammography is used for early breast cancer detection in asymptomatic
women and still remains the gold standard imaging modality. However, population …

Identifying germline BRCA1/2 mutation carriers is vital for reducing their risk of breast and
ovarian cancer. To derive a serum miRNA-based diagnostic test we used samples from 653 …

Importance Magnetic resonance imaging (MRI) surveillance is offered to women with a
pathogenic variant in theBRCA1orBRCA2gene who face a high lifetime risk of breast …

Genomic medicine is expanding from a focus on diagnosis at the patient level to prevention
at the population level given the ongoing under-ascertainment of high-risk and actionable …

Women at risk for hereditary breast and ovarian cancer syndromes are frequently seen in
primary care and gynecology clinics. They present with a distinctive set of clinical and …

With widespread testing for susceptibility genes, increasing numbers of women are being
identified to carry a mutation in one of many genes which renders them susceptible to …

Purpose Women at increased familial breast cancer risk have been offered screening
starting at an earlier age and increased frequency than national Screening Programmes for …

Background: According to the International Agency for Research on Cancer, ongoing
demographic changes will lead to an increase in the number of deaths from breast cancer …

Background The purpose of this study was to estimate the cumulative risks of all cancers in
women from 50 to 75 years of age with a BRCA1 or BRCA2 pathogenic variant. Methods …