Intrarenal autoregulatory mechanisms maintain renal blood flow (RBF) and glomerular
filtration rate (GFR) independent of renal perfusion pressure (RPP) over a defined range (80 …

Since the crucial evolutionary change from an aqueous to a terrestrial environment, all living
organisms address the primordial task of equilibrating the ingestion/production of water and …

Background: Recent studies reported increased (Pro) renin receptor (PRR) expression
during low-salt intake. We hypothesized that PRR plays a role in regulation of renal …

This study investigated the effects of heme oxygenase 1 (HO-1) on thrombomodulin (TM)
and endothelial protein C receptor (EPCR) expression in sepsis-induced kidney injury. The …

Bilirubin is generated from the breakdown of heme by heme oxygenase and the reduction of
biliverdin by the enzyme biliverdin reductase. Several large population studies have …

The vectorial transport of Na+ across epithelia is crucial for the maintenance of Na+ and
water homeostasis in organs such as the kidneys, lung, or intestine. Dysregulated Na+ …

Three gases comprising nitric oxide, carbon monoxide and hydrogen sulphide, collectively
are termed gasotransmitters. The gasotransmitters control several physiological functions in …

Heme oxygenase (HO), a heat shock protein containing hemoglobin, is an important
enzyme in heme catabolism. It is involved in cell homeostasis and has anti-inflammatory …

Background: The incidence of patent ductus arteriosus is known to be higher in premature
neonates with infection than in those without infection. However, the detailed mechanism …

Recurring insulin‐induced hypoglycaemia (RIIH) often occurs during the therapeutic
management of insulin‐dependent diabetes mellitus. Controversy currently exists in the …