[HTML][HTML] Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori

NR Salama, ML Hartung, A Müller - Nature Reviews Microbiology, 2013 - nature.com
The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes
approximately 50% of the human population, but only causes overt gastric disease in a …

Immunological Perspective: Helicobacter pylori Infection and Gastritis

H Yang, B Hu - Mediators of inflammation, 2022 - Wiley Online Library
Helicobacter pylori is a spiral‐shaped gram‐negative bacterium. Its infection is mainly
transmitted via oral‐oral and fecal‐oral routes usually during early childhood. It can achieve …

[HTML][HTML] Increased Abundance of Clostridium and Fusobacterium in Gastric Microbiota of Patients with Gastric Cancer in Taiwan

YY Hsieh, SY Tung, HY Pan, CW Yen, HW Xu, YJ Lin… - Scientific reports, 2018 - nature.com
Helicobacter pylori is recognised as a main risk factor for gastric cancer. However,
approximately half of the patients with gastritis are negative for H. pylori infection, and the …

Pathogenesis of Helicobacter pylori Infection

S Backert, M Clyne - Helicobacter, 2011 - Wiley Online Library
Helicobacter pylori infections and clinical outcome are dependent on sophisticated
interactions between the bacteria and its host. Crucial bacterial factors associated with …

[HTML][HTML] Pattern-recognition receptors and gastric cancer

N Castaño-Rodríguez, NO Kaakoush… - Frontiers in …, 2014 - frontiersin.org
Chronic inflammation has been associated with an increased risk of several human
malignancies, a classic example being gastric adenocarcinoma (GC). Development of GC is …

[HTML][HTML] The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis

G Posselt, S Backert, S Wessler - Cell Communication and Signaling, 2013 - Springer
Infections with the human pathogen Helicobacter pylori (H. pylori) can lead to severe gastric
diseases ranging from chronic gastritis and ulceration to neoplastic changes in the stomach …

Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells

A Elmi, E Watson, P Sandu, O Gundogdu… - Infection and …, 2012 - Am Soc Microbiol
Campylobacter jejuni is the most prevalent cause of food-borne gastroenteritis in the
developed world; however, the molecular basis of pathogenesis is unclear. Secretion of …

[HTML][HTML] Molecular mechanisms of gastric epithelial cell adhesion and injection of CagA by Helicobacter pylori

S Backert, M Clyne, N Tegtmeyer - Cell Communication and Signaling, 2011 - Springer
Helicobacter pylori is a highly successful pathogen uniquely adapted to colonize humans.
Gastric infections with this bacterium can induce pathology ranging from chronic gastritis …

The Human Gastric Pathogen Helicobacter pylori and Its Association with Gastric Cancer and Ulcer Disease

B Bauer, TF Meyer - Ulcers, 2011 - Wiley Online Library
With the momentous discovery in the 1980′ s that a bacterium, Helicobacter pylori, can
cause peptic ulcer disease and gastric cancer, antibiotic therapies and prophylactic …

[HTML][HTML] Role of Toll-like receptors in Helicobacter pylori infection and immunity

SM Smith - World journal of gastrointestinal pathophysiology, 2014 - ncbi.nlm.nih.gov
The gram-negative bacterium Helicobacter pylori (H. pylori) infects the stomachs of
approximately half of the world's population. Although infection induces an immune …