Cannabis-related disorders and toxic effects
DA Gorelick - New England Journal of Medicine, 2023 - Mass Medical Soc
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The endocannabinoid system as a putative target for the development of novel drugs for the treatment of psychiatric illnesses
Cannabis is well established to impact affective states, emotion and perceptual processing,
primarily through its interactions with the endocannabinoid system. While cannabis use is …
primarily through its interactions with the endocannabinoid system. While cannabis use is …
Factors that impact the pharmacokinetic and pharmacodynamic effects of cannabis: a review of human laboratory studies
Abstract Purpose of Review With cannabis legalization expanding throughout the world, an
unprecedented number of people now have access to legal cannabis. This expanded …
unprecedented number of people now have access to legal cannabis. This expanded …
Molecular alterations of the endocannabinoid system in psychiatric disorders
D Navarro, A Gasparyan, F Navarrete… - International journal of …, 2022 - mdpi.com
The therapeutic benefits of the current medications for patients with psychiatric disorders
contrast with a great variety of adverse effects. The endocannabinoid system (ECS) …
contrast with a great variety of adverse effects. The endocannabinoid system (ECS) …
[HTML][HTML] Synaptic changes induced by cannabinoid drugs and cannabis use disorder
SM Augustin, DM Lovinger - Neurobiology of Disease, 2022 - Elsevier
The legalization of cannabis in many countries, as well as the decrease in perceived risks of
cannabis, have contributed to the increase in cannabis use medicinally and recreationally …
cannabis, have contributed to the increase in cannabis use medicinally and recreationally …
Effects of cannabidiol on anandamide levels in individuals with cannabis use disorder: findings from a randomised clinical trial for the treatment of cannabis use …
Cannabidiol (CBD) has shown promise in treating psychiatric disorders, including cannabis
use disorder–a major public health burden with no approved pharmacotherapies. However …
use disorder–a major public health burden with no approved pharmacotherapies. However …
Biomarkers of the endocannabinoid system in substance use disorders
F Navarrete, MS García-Gutiérrez, A Gasparyan… - Biomolecules, 2022 - mdpi.com
Despite substance use disorders (SUD) being one of the leading causes of disability and
mortality globally, available therapeutic approaches remain ineffective. The difficulty in …
mortality globally, available therapeutic approaches remain ineffective. The difficulty in …
The relationship between circulating endogenous cannabinoids and the effects of smoked cannabis
T Kearney-Ramos, ES Herrmann… - Cannabis and …, 2023 - liebertpub.com
Background: The endogenous cannabinoid system (ECS), including the endocannabinoids
(eCBs), anandamide (AEA), and 2-arachidonoylglycerol (2-AG), plays an integral role in …
(eCBs), anandamide (AEA), and 2-arachidonoylglycerol (2-AG), plays an integral role in …
Sex differences in endocannabinoid tone in a pilot study of cannabis use disorder and acute cannabis abstinence
Cannabis use disorder (CUD) presents differently in men and women, particularly in
symptoms of cannabis withdrawal. Novel pharmacotherapeutic interventions for CUD, such …
symptoms of cannabis withdrawal. Novel pharmacotherapeutic interventions for CUD, such …
Cannabis self-administration in the human laboratory: a scoping review of ad libitum studies
Cannabis self-administration studies may be helpful for identifying factors that influence
cannabis consumption and subjective response to cannabis. Additionally, these paradigms …
cannabis consumption and subjective response to cannabis. Additionally, these paradigms …