The evolution of poxvirus vaccines

L Sánchez-Sampedro, B Perdiguero, E Mejías-Pérez… - Viruses, 2015 - mdpi.com
After Edward Jenner established human vaccination over 200 years ago, attenuated
poxviruses became key players to contain the deadliest virus of its own family: Variola virus …

[HTML][HTML] Chagas disease in the 21st century: a public health success or an emerging threat?

KM Bonney - Parasite, 2014 - ncbi.nlm.nih.gov
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major public
health burden in Latin America and a potentially serious emerging threat to a number of …

Terminally modified RNA

T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
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Modified polynucleotides for the production of biologics and proteins associated with human disease

S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
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Modified polynucleotides for the production of secreted proteins

T Chakraborty, A De Fougerolles - US Patent 9,192,651, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
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Engineered nucleic acids and methods of use thereof

S Bancel, JP Schrum, A Aristarkhov - US Patent 9,464,124, 2016 - Google Patents
A61K48/0075—Medicinal preparations containing genetic material which is inserted into
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …

In vivo production of proteins

S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins

T Chakraborty, A De Fougerolles - US Patent 9,303,079, 2016 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

Compositions and methods of altering cholesterol levels

SG Hoge, A De Fougerolles, JL Ellsworth - US Patent 8,980,864, 2015 - Google Patents
2014-03-21 Assigned to MODERNA THERAPEUTICS, INC. reassignment MODERNA
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Delivery and formulation of engineered nucleic acids

A De Fougerolles, SM Elbashir - US Patent 9,533,047, 2017 - Google Patents
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