Objective Chromosome 22q11. 2 deletion syndrome is a neurogenetic disorder associated
with high rates of schizophrenia and other psychiatric conditions. The authors report what is …

Abstract 22q11. 2 deletion syndrome (22q11. 2DS) is the most common chromosomal
microdeletion disorder, estimated to result mainly from de novo non-homologous meiotic …

Background: Although pathogenic 22q11. 2 deletions are an important cause of
developmental delays and lifelong disease burden, their variable and complex clinical …

This review aimed to update the clinical practice guidelines for managing adults with 22q11.
2 deletion syndrome (22q11. 2DS). The 22q11. 2 Society recruited expert clinicians …

Summary Chromosome 22q11. 2 deletion syndrome is the most common microdeletion
syndrome in humans. The effects are protean and highly variable, making a unified …

Abstract Chromosome 22q11. 21 contains a cluster of low-copy repeats (LCRs), referred to
as LCR22A-H, that mediate meiotic non-allelic homologous recombination, resulting in …

Recurrent copy number variations (CNVs) are common causes of neurodevelopmental
disorders (NDDs) and associated with a range of psychiatric traits. These CNVs occur at …

DNA replication precisely duplicates the genome to ensure stable inheritance of genetic
information. Impaired licensing of origins of replication during the G 1 phase of the cell cycle …

Chromosome 22q11 is characterized by the presence of chromosome-specific low-copy
repeats or segmental duplications. This region of the chromosome is very unstable and …

Recurrent deletions and duplications at chromosomal region 16p11. 2 are a major genetic
contributor to autism but also associate with a wider range of pediatric diagnoses, including …