Global protein dynamics as communication sensors in peptide synthetase domains
Biological activity is governed by the timely redistribution of molecular interactions, and static
structural snapshots often appear insufficient to provide the molecular determinants that …
structural snapshots often appear insufficient to provide the molecular determinants that …
Decoding Atomic Addresses: Solution NMR Resonance Assignment of Proteins
Resonance assignment signifies the process through which an NMR signal at a certain
resonance frequency, or chemical shift, is correlated to a specific atom in a protein. The …
resonance frequency, or chemical shift, is correlated to a specific atom in a protein. The …
In-cell Structural Biology Through the Integration of Solution NMR Spectroscopy and Computational Science
Y Ito, T Ikeya, K Inomata - 2023 - books.rsc.org
The intracellular environment is highly crowded (molecular crowding) and differs
significantly from the environment in dilute solutions that we usually use in biochemical …
significantly from the environment in dilute solutions that we usually use in biochemical …
EXPLORING MUTAGENESIS AND DEVELOPING NOVEL NUCLEAR MAGNETIC RESONANCE TECHNIQUES TO STUDY NONRIBOSOMAL PEPTIDE …
KA Marincin - 2023 - jscholarship.library.jhu.edu
Nonribosomal peptide synthetases (NRPSs) are a class of enzymes that produce complex
natural products with applications in medicine and industry. Their modular architecture is …
natural products with applications in medicine and industry. Their modular architecture is …