Tumor-targeted nano-delivery system of therapeutic RNA
M Wang, J Zhao, H Jiang, X Wang - Materials horizons, 2022 - pubs.rsc.org
The birth of RNAi technology has pioneered actionability at the molecular level. Compared
to DNA, RNA is less stable and therefore requires more demanding delivery vehicles. With …
to DNA, RNA is less stable and therefore requires more demanding delivery vehicles. With …
Revealing local molecular distribution, orientation, phase separation, and formation of domains in artificial lipid layers: Towards comprehensive characterization of …
K Sofińska, D Lupa, A Chachaj-Brekiesz… - Advances in Colloid and …, 2022 - Elsevier
Lipids, together with molecules such as DNA and proteins, are one of the most relevant
systems responsible for the existence of life. Selected lipids are able to assembly into …
systems responsible for the existence of life. Selected lipids are able to assembly into …
How unsaturated fatty acids and plant stanols affect sterols plasma level and cellular membranes? Review on model studies involving the Langmuir monolayer …
JLF Rodríguez, P Dynarowicz-Latka… - Chemistry and Physics of …, 2020 - Elsevier
The Langmuir monolayer technique has long been known for its usefulness to study the
interaction between molecules and mimic cellular membranes to understand the mechanism …
interaction between molecules and mimic cellular membranes to understand the mechanism …
[HTML][HTML] Can oxysterols work in anti-glioblastoma therapy? Model studies complemented with biological experiments
A Wnętrzak, A Kubisiak, A Filiczkowska… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Despite the progress made in recent years in the field of oncology, the results of
glioblastoma treatment remain unsatisfactory. In this paper, cholesterol derivatives …
glioblastoma treatment remain unsatisfactory. In this paper, cholesterol derivatives …
[HTML][HTML] The effects of cholesterol oxidation on erythrocyte plasma membranes: a monolayer study
BD Lechner, P Smith, B McGill, S Marshall, JL Trick… - Membranes, 2022 - mdpi.com
Cholesterol plays a key role in the molecular and mesoscopic organisation of lipid
membranes and it is expected that changes in its molecular structure (eg, through …
membranes and it is expected that changes in its molecular structure (eg, through …
Interaction of dicentrinone, an antitrypanosomal aporphine alkaloid isolated from Ocotea puberula (Lauraceae), in cell membrane models at the air-water interface
H Barbosa, RLCG da Silva, TA Costa-Silva… - Bioorganic …, 2020 - Elsevier
In the present work, the oxoaporphine alkaloid dicentrinone was isolated, for the first time,
from leaves of Ocotea puberula (Lauraceae). This alkaloid exhibited antiparasitic activity …
from leaves of Ocotea puberula (Lauraceae). This alkaloid exhibited antiparasitic activity …
Different effects of oxysterols on a model lipid raft–langmuir monolayer study complemented with theoretical calculations
A Wnętrzak, A Chachaj–Brekiesz, A Stępniak… - Chemistry and Physics …, 2022 - Elsevier
Abstract Three oxysterols (7β-hydroxycholesterol; 7β-OH, 7-ketocholesterol; 7-K and 25-
hydroxycholesterol, 25-OH) differing in the site of oxidation (ring system versus chain) and …
hydroxycholesterol, 25-OH) differing in the site of oxidation (ring system versus chain) and …
[HTML][HTML] The Effect of Selected Flavonoids and Lipoic Acid on Natural and Model Cell Membranes: Langmuir and Microelectrophoretic Methods
P Laszuk, W Urbaniak, AD Petelska - Molecules, 2023 - mdpi.com
The influence of kaempferol (K), myricetin (M) and lipoic acid (LA) on the properties of
natural erythrocytes, isolated from animal blood and biological membrane models …
natural erythrocytes, isolated from animal blood and biological membrane models …
Molecular insight into neurodegeneration–Langmuir monolayer study on the influence of oxysterols on model myelin sheath
A Chachaj-Brekiesz, A Wnętrzak, S Włodarska… - The Journal of Steroid …, 2020 - Elsevier
Systematic studies on the influence of selected ring–oxidized (7α–hydroxycholesterol, 7α−
OH; 7β–hydroxycholesterol, 7β− OH; 7–ketocholesterol, 7–K) and chain–oxidized (25− OH) …
OH; 7β–hydroxycholesterol, 7β− OH; 7–ketocholesterol, 7–K) and chain–oxidized (25− OH) …
[HTML][HTML] Effect of 7-ketocholesterol incorporation on substrate binding affinity and turnover rate of the organic cation transporter 2 (OCT2)
F Xiu, L Console, C Indiveri, S Su, T Wang… - Biochemical …, 2024 - Elsevier
The organic cation transporter 2 (OCT2) is pivotal in the renal elimination of several
positively charged molecules. OCT2 mode of transport is profoundly influenced by the level …
positively charged molecules. OCT2 mode of transport is profoundly influenced by the level …