Hydroxycinnamic acids and their derivatives: Cosmeceutical significance, challenges and future perspectives, a review
Bioactive compounds from natural sources, due to their widely-recognized benefits, have
been exploited as cosmeceutical ingredients. Among them, phenolic acids emerge with a …
been exploited as cosmeceutical ingredients. Among them, phenolic acids emerge with a …
Nrf2 as regulator of innate immunity: A molecular Swiss army knife!
M Battino, F Giampieri, F Pistollato, A Sureda… - Biotechnology …, 2018 - Elsevier
Organisms are constantly exposed to a broad range of pathological and stress-inducing
agents, allergens and environmental chemicals that can induce infections, toxicity or other …
agents, allergens and environmental chemicals that can induce infections, toxicity or other …
Anti-neuroinflammatory effects of fucoxanthin via inhibition of Akt/NF-κB and MAPKs/AP-1 pathways and activation of PKA/CREB pathway in lipopolysaccharide …
Microglia play a critical role in controlling the homeostasis of the brain, but over-activated
microglia secrete pro-inflammatory mediators and cytokines, which induce neuronal cell …
microglia secrete pro-inflammatory mediators and cytokines, which induce neuronal cell …
Piperine attenuates lipopolysaccharide (LPS)-induced inflammatory responses in BV2 microglia
C Wang-Sheng, A Jie, L Jian-Jun, H Lan… - International …, 2017 - Elsevier
Piperine, the chief alkaloid isolated from Piper nigrum, has been known to have anti-
inflammatory effect. However, the effects of piperine on neuroinflammation have not been …
inflammatory effect. However, the effects of piperine on neuroinflammation have not been …
Involvement of the Nrf2/HO-1 signaling pathway in sulfuretin-induced protection against amyloid beta25–35 neurotoxicity
Sulfuretin, one of the major flavonoid glycosides found in the stem bark of Albizzia julibrissin
and heartwood of Rhus verniciflua, is a known anti-oxidant. We previously demonstrated …
and heartwood of Rhus verniciflua, is a known anti-oxidant. We previously demonstrated …
[HTML][HTML] Piperlongumine inhibits neuroinflammation via regulating NF-κB signaling pathways in lipopolysaccharide-stimulated BV2 microglia cells
Inflammatory processes in the central nervous system are feature among biological
reactions to harmful stimuli such as pathogens and damaged cells. In resting conditions …
reactions to harmful stimuli such as pathogens and damaged cells. In resting conditions …
(−)-Syringaresinol suppressed LPS-induced microglia activation via downregulation of NF-κB p65 signaling and interaction with ERβ
L Zhang, X Jiang, J Zhang, H Gao, L Yang, D Li… - International …, 2021 - Elsevier
Albiziae Cortex (AC) is a well-known traditional Chinese medicine with sedative-hypnotic
effects and neuroprotective ability. However, the bioactive components of AC responsible for …
effects and neuroprotective ability. However, the bioactive components of AC responsible for …
5-Aminolevulinic acid combined with ferrous iron enhances the expression of heme oxygenase-1
Y Nishio, M Fujino, M Zhao, T Ishii, M Ishizuka… - International …, 2014 - Elsevier
Aminolevulinic acid (5-ALA) is the naturally occurring metabolic precursor of heme. Heme
negatively regulates the Maf recognition element (MARE) binding-and repressing-activity of …
negatively regulates the Maf recognition element (MARE) binding-and repressing-activity of …
Potent anti-inflammatory and analgesic actions of the chloroform extract of Dendropanax morbifera mediated by the Nrf2/HO-1 pathway
Dendropanax morbifera LEVEILLE (DP) has been used in traditional Korean medicines to
treat a variety of inflammatory diseases. Although the in vitro anti-inflammatory potential of …
treat a variety of inflammatory diseases. Although the in vitro anti-inflammatory potential of …
β-Defensin 129 attenuates bacterial endotoxin-induced inflammation and intestinal epithelial cell apoptosis
K Xie, H Xie, G Su, D Chen, B Yu, X Mao… - Frontiers in …, 2019 - frontiersin.org
Defensins have attracted considerable research interest worldwide because of their
potential to serve as a substitute for antibiotics. In this study, we characterized a novel …
potential to serve as a substitute for antibiotics. In this study, we characterized a novel …