Bioactive compounds from natural sources, due to their widely-recognized benefits, have
been exploited as cosmeceutical ingredients. Among them, phenolic acids emerge with a …

Organisms are constantly exposed to a broad range of pathological and stress-inducing
agents, allergens and environmental chemicals that can induce infections, toxicity or other …

Microglia play a critical role in controlling the homeostasis of the brain, but over-activated
microglia secrete pro-inflammatory mediators and cytokines, which induce neuronal cell …

Piperine, the chief alkaloid isolated from Piper nigrum, has been known to have anti-
inflammatory effect. However, the effects of piperine on neuroinflammation have not been …

Sulfuretin, one of the major flavonoid glycosides found in the stem bark of Albizzia julibrissin
and heartwood of Rhus verniciflua, is a known anti-oxidant. We previously demonstrated …

Inflammatory processes in the central nervous system are feature among biological
reactions to harmful stimuli such as pathogens and damaged cells. In resting conditions …

Albiziae Cortex (AC) is a well-known traditional Chinese medicine with sedative-hypnotic
effects and neuroprotective ability. However, the bioactive components of AC responsible for …

Aminolevulinic acid (5-ALA) is the naturally occurring metabolic precursor of heme. Heme
negatively regulates the Maf recognition element (MARE) binding-and repressing-activity of …

Dendropanax morbifera LEVEILLE (DP) has been used in traditional Korean medicines to
treat a variety of inflammatory diseases. Although the in vitro anti-inflammatory potential of …

Defensins have attracted considerable research interest worldwide because of their
potential to serve as a substitute for antibiotics. In this study, we characterized a novel …