In silico clinical trials (ISCTs) are an emerging method in modeling and simulation where
medical interventions are evaluated using computational models of patients. ISCTs have the …

Hemodynamic factors, induced by pulsatile blood flow, play a crucial role in vascular health
and diseases, such as the initiation and progression of atherosclerosis. Computational fluid …

Background Newtonian fluid model has been commonly applied in simulating cerebral
blood flow in intracranial atherosclerotic stenosis (ICAS) cases using computational fluid …

Computational modeling and investigation have become increasingly useful in assessing
the hemodynamic and structural factors that contribute to aneurysm rupture, particularly …

Purpose Advanced morphology analysis and image-based hemodynamic simulations are
increasingly used to assess the rupture risk of intracranial aneurysms (IAs). However, the …

Computational modeling of cerebral aneurysms, derived from clinical 3D angiography, has
become widespread over the past 15 years. While such “image-based” or “patient-specific” …

Recognition of the aneurysm rupture risk after endovascular treatments is important for the
evaluation of the applied treatment technique. In this paper, the role of the stent in the …

Computational blood flow modeling in intracranial aneurysms (IAs) has enormous potential
for the assessment of highly resolved hemodynamics and derived wall stresses. This results …

OBJECTIVE Aneurysm wall enhancement (AWE) on 3D vessel wall MRI (VWMRI) has been
suggested as an imaging biomarker for intracranial aneurysms (IAs) at higher risk of rupture …

Computational fluid dynamics (CFD) simulations are increasingly utilised to evaluate
intracranial aneurysm (IA) haemodynamics to aid in the prediction of morphological changes …