Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

The global pandemic of obesity and type 2 diabetes is often causally linked to marked
changes in diet and lifestyle; namely marked increases in dietary intakes of high energy …

Epigenetic modifications are among the most important mechanisms by which
environmental factors can influence early cellular differentiation and create new phenotypic …

Many studies in humans have shown that adverse experience in early life is associated with
accelerated reproductive timing, and there is comparative evidence for similar effects in …

Overweight and obesity during pregnancy have been associated with increased birth
weight, childhood obesity, and noncommunicable diseases in the offspring, leading to a …

The term 'life course epidemiology'was coined in 1997 with the publication of the first edition
of A Life Course Approach to Chronic Disease Epidemiology. 1 This book reviewed the pre …

Considerable epidemiological, experimental and clinical data have amassed showing that
the risk of developing disease in later life is dependent on early life conditions, mainly …

A child's sense of control over life and health outcomes as well as perceptions of the world
as fair, equal, and just are significantly influenced by his or her social experiences and …

The incidence of obesity and overweight has reached epidemic proportions in the
developed world as well as in those countries transitioning to first world economies, and this …

Experimental animal findings suggest that early stress and glucocorticoid exposure may
program the function of the hypothalamic–pituitary–adrenal (HPA) axis in the offspring. The …