Cytokines are soluble proteins that allow for communication between cells and the external
environment. Interferon (IFN) alpha, the first cytokine to be produced by recombinant DNA …

Gap junctions are membrane structures made of intercellular channels which permit the
diffusion from cytoplasm to cytoplasm of small hydrophilic molecules. Nearly 40 years ago …

Despite the pivotal role of natural killer (NK) cells in defenses against tumors, their
exploitation in cancer treatment is still limited due to their reduced ability to reaching tumor …

Activation of the Ras/Raf/mitogen-activated protein kinase kinase/mitogen-activated protein
(MAP) kinase signaling cascade is initiated by activation of growth factor receptors and …

Tunneling nanotubes (TnTs) represent a novel mechanism by which intercellular
components such as proteins, Golgi vesicles, and mitochondria can be transferred from cell …

The chemopreventive effects of two xanthophylls, astaxanthin (AX) and canthaxanthin (CX),
on urinary bladder carcino genesis induced by N-butyl-N (4-hydroxybutyl) nitrosamine (OH …

The hypothesis, that gap junctional intercellular communication plays a key role in
carcinogenesis and more generally in growth control was formulated nearly 40 years ago …

The modulating effects of dietary feeding of two xanthophylls, astaxanthin (AX) and
canthaxanthin (CX) during the postinitiation phase on colon carcinogenesis initiated with …

Chemically induced cancer is a multi-step process involving damage to the genome initially
followed by clonal expansion of the DNA damaged cell eventually leading to a neoplasm …

Antiarrhythmic peptides enhance gap junction current in pairs of cardiomyocytes and
coupling in cardiac tissue. To elucidate the underlying mechanisms, we investigated the …