CD8 T cells play crucial roles in immune surveillance and defense against infections and
cancer. After encountering antigenic stimulation, naïve CD8 T cells differentiate and acquire …

Eicosanoids comprise a group of oxidation products of arachidonic and 5, 8, 11, 14, 17-
eicosapentaenoic acids formed by oxygenases and downstream enzymes. The two major …

Mast cell products and high levels of type 2 cytokines are associated with severe dengue
disease. Group 2 innate lymphoid cells (ILC2) are type-2 cytokine-producing cells that are …

Objective Asthma is a chronic lung disease comprising multiple endotypes and
characterized by periodic exacerbations. A diverse array of T cells has been found to …

Abstract Prostaglandin D 2 (PGD 2) synthesis is closely associated with the innate immune
response mediated by pattern recognition receptors (PPRs). We determined PGD 2 …

Background Single-cell sequencing provides detailed insights into biological processes
including cell differentiation and identity. While providing deep cell-specific information, the …

Bioactive lipids, such as lysophospholipids, ceramides, and eicosanoids and related
mediators, have been demonstrated to be involved in inflammation. We aimed to investigate …

Background Allergic conjunctivitis (AC) afflicts a significant portion of the global populace.
Yet, its metabolic foundations remain largely unexplored. Methods We applied Mendelian …

Purpose: The exact etiology of Postural Orthostatic Tachycardia Syndrome (POTS) is still
unknown but is likely heterogeneous and multifaceted, involving autoimmune, neuropathic …

Dengue is a mosquito borne tropical infection caused by the dengue virus with a dramatic
global spread over the last few decades. Dengue infection can present as dengue fever (DF) …