A global accounting of medically significant scorpions: Epidemiology, major toxins, and comparative resources in harmless counterparts

MJ Ward, SA Ellsworth, GS Nystrom - Toxicon, 2018 - Elsevier
Scorpions are an ancient and diverse venomous lineage, with over 2200 currently
recognized species. Only a small fraction of scorpion species are considered harmful to …

Snake venomics: fundamentals, recent updates, and a look to the next decade

CH Tan - Toxins, 2022 - mdpi.com
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …

Terrestrial venomous animals, the envenomings they cause, and treatment perspectives in the Middle East and North Africa

TP Jenkins, S Ahmadi, MA Bittenbinder… - PLoS neglected …, 2021 - journals.plos.org
The Middle East and Northern Africa, collectively known as the MENA region, are inhabited
by a plethora of venomous animals that cause up to 420,000 bites and stings each year. To …

Evaluating the performance of de novo assembly methods for venom-gland transcriptomics

ML Holding, MJ Margres, AJ Mason, CL Parkinson… - Toxins, 2018 - mdpi.com
Venom-gland transcriptomics is a key tool in the study of the evolution, ecology, function,
and pharmacology of animal venoms. In particular, gene-expression variation and coding …

Scorpion venomics: a 2019 overview

JI Cid-Uribe, JI Veytia-Bucheli… - Expert review of …, 2020 - Taylor & Francis
Introduction: A few scorpions are dangerous to humans. Their medical relevance was the
initial driving force for venom research. By classical biochemistry and molecular cloning …

Scorpion venom as a source of antimicrobial peptides: overview of biomolecule separation, analysis and characterization methods

S Nasr, A Borges, C Sahyoun, R Nasr, R Roufayel… - Antibiotics, 2023 - mdpi.com
Scorpion venoms have long captivated scientific researchers, primarily due to the potency
and specificity of the mechanism of action of their derived components. Among other …

An integrated transcriptomic and proteomic approach to identify the main Torymus sinensis venom components

C Scieuzo, R Salvia, A Franco, M Pezzi, F Cozzolino… - Scientific Reports, 2021 - nature.com
During oviposition, ectoparasitoid wasps not only inject their eggs but also a complex
mixture of proteins and peptides (venom) in order to regulate the host physiology to benefit …

Differential venom gland gene expression analysis of juvenile and adult scorpions Androctonus crassicauda

F Salabi, H Jafari - BMC genomics, 2022 - Springer
Abstract Background The Androctonus crassicauda, belonging to the genus Androctonus of
the family Buthidae, is the most venomous scorpion in Middle East countries. However, the …

Comparative venom-gland transcriptomics and venom proteomics of four Sidewinder Rattlesnake (Crotalus cerastes) lineages reveal little differential expression …

EP Hofmann, RM Rautsaw, JL Strickland… - Scientific Reports, 2018 - nature.com
Abstract Changes in gene expression can rapidly influence adaptive traits in the early
stages of lineage diversification. Venom is an adaptive trait comprised of numerous toxins …

The enzymatic core of scorpion venoms

G Delgado-Prudencio, JI Cid-Uribe, JA Morales… - Toxins, 2022 - mdpi.com
Enzymes are an integral part of animal venoms. Unlike snakes, in which enzymes play a
primary role in envenomation, in scorpions, their function appears to be ancillary in most …