[HTML][HTML] Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: pathogenic bacteria and altered …
PL Lakatos, S Fischer, L Lakatos, I Gal… - World Journal of …, 2006 - ncbi.nlm.nih.gov
The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various
environmental and host (eg genetic-, epithelial-, immune and non-immune) factors are …
environmental and host (eg genetic-, epithelial-, immune and non-immune) factors are …
Is the incidence and prevalence of inflammatory bowel diseases increasing in Eastern Europe?
L Lakatos, PL Lakatos - Postgraduate medical journal, 2006 - academic.oup.com
Limited data are available on the frequency of inflammatory bowel diseases in East
European countries. A recent study from Hungary reported an increasing incidence rate for …
European countries. A recent study from Hungary reported an increasing incidence rate for …
Fusobacterium Detected in Colonic Biopsy and Clinicopathological Features of Ulcerative Colitis in Japan
T Tahara, T Shibata, T Kawamura, M Okubo… - Digestive diseases and …, 2015 - Springer
Abstract Background and Aims Fusobacterium species are part of the gut microbiome in
humans, but some species have been recognized as opportunistic pathogens implicated in …
humans, but some species have been recognized as opportunistic pathogens implicated in …
Association study of common genetic variants in pre-microRNAs in patients with ulcerative colitis
M Okubo, T Tahara, T Shibata, H Yamashita… - Journal of clinical …, 2011 - Springer
Background Common single-nucleotide polymorphisms (SNPs) in microRNAs (miRNA)
have been shown to be associated with susceptibility to several human diseases. We …
have been shown to be associated with susceptibility to several human diseases. We …
DNA methylation status of epithelial-mesenchymal transition (EMT)-related genes is associated with severe clinical phenotypes in ulcerative colitis (UC)
T Tahara, T Shibata, M Okubo, T Ishizuka… - PLoS …, 2014 - journals.plos.org
Background Epithelial-to-mesenchymal transition (EMT) is a phenomenon that allows the
conversion of adherent epithelial cells to a mesenchymal cell phenotype, which enhances …
conversion of adherent epithelial cells to a mesenchymal cell phenotype, which enhances …
Association of miRNA-146a rs2910164 and miRNA-196 rs11614913 polymorphisms in patients with ulcerative colitis: A meta-analysis and review
Z Li, Y Wang, Y Zhu - Medicine, 2018 - journals.lww.com
Background: It has been reported that the single nucleotide polymorphisms (SNPs) miRNA-
196 (miR-196) rs11614913 and miRNA-146a (miR-146a) rs2910164 are related to …
196 (miR-196) rs11614913 and miRNA-146a (miR-146a) rs2910164 are related to …
Telomere length in non-neoplastic colonic mucosa in ulcerative colitis (UC) and its relationship to the severe clinical phenotypes
T Tahara, T Shibata, M Okubo, T Kawamura… - Clinical and …, 2015 - Springer
Telomere shortening occurs with human aging in many organs and tissues and is
accelerated by rapid cell turnover and oxidative injury. To clarify the clinical importance of …
accelerated by rapid cell turnover and oxidative injury. To clarify the clinical importance of …
吸烟对克罗恩病的影响
任蔚虹， 徐群燕 - 国际护理学杂志, 2006 - cqvip.com
克罗恩病(Crohn's disease, CD) 是一种病因尚不十分清楚的胃肠道慢性, 炎性, 肉芽肿性疾病.
近10 年来, 该病全球发病率成倍上升. 一般认为是环境因素和遗传因素共同作用引发免疫异常 …
近10 年来, 该病全球发病率成倍上升. 一般认为是环境因素和遗传因素共同作用引发免疫异常 …
炎症性肠病患者外周血CD4^+ CD25^+ Treg 细胞及其特异标志物Foxp3 表达水平的研究
孙可歆， 李永哲， 赵臣， 刘定华， 胡朝军， 佟大伟… - 中国免疫学杂志, 2008 - cqvip.com
目的: 通过检测炎症性肠病(IBD) 不同病期患者以及对照组外周血CD4^+ CD25^+ Treg
及其特异标志物Foxp3 的表达, 来分析与IBD 疾病活动性关系, 探讨CD4^+ CD25^+ Treg …
及其特异标志物Foxp3 的表达, 来分析与IBD 疾病活动性关系, 探讨CD4^+ CD25^+ Treg …
Successful autologous haemopoietic stem cell transplantation in severe, therapy-resistant childhood-onset Crohn's disease. Report on the first case in Hungary
G Kriván, D Szabó, K Kállay, G Benyó, C Kassa… - Orvosi …, 2014 - akjournals.com
The biological therapy of Crohn's disease, such as infliximab is a powerful approach in the
therapy of inflammatory bowel diseases. However, in some patients with aggressive disease …
therapy of inflammatory bowel diseases. However, in some patients with aggressive disease …