[HTML][HTML] Understanding and improving recruitment to randomised controlled trials: qualitative research approaches
Context The importance of evidence from randomised trials is now widely recognised,
although recruitment is often difficult. Qualitative research has shown promise in identifying …
although recruitment is often difficult. Qualitative research has shown promise in identifying …
[HTML][HTML] Different types of implants for reconstructive breast surgery
Background Breast cancer is the most common cancer in women worldwide, and is a
leading cause of cancer death among women. Prophylactic or curative mastectomy is often …
leading cause of cancer death among women. Prophylactic or curative mastectomy is often …
Short-term safety outcomes of mastectomy and immediate implant-based breast reconstruction with and without mesh (iBRA): a multicentre, prospective cohort study
Background Use of biological or synthetic mesh might improve outcomes of immediate
implant-based breast reconstruction—breast reconstruction with implants or expanders at …
implant-based breast reconstruction—breast reconstruction with implants or expanders at …
Development of a core outcome set for research and audit studies in reconstructive breast surgery
Background Appropriate outcome selection is essential if research is to guide decision-
making and inform policy. Systematic reviews of the clinical, cosmetic and patient-reported …
making and inform policy. Systematic reviews of the clinical, cosmetic and patient-reported …
Conveying equipoise during recruitment for clinical trials: qualitative synthesis of clinicians' practices across six randomised controlled trials
Background Randomised controlled trials (RCTs) are essential for evidence-based
medicine and increasingly rely on front-line clinicians to recruit eligible patients. Clinicians' …
medicine and increasingly rely on front-line clinicians to recruit eligible patients. Clinicians' …
Systematic review and critical appraisal of the impact of acellular dermal matrix use on the outcomes of implant-based breast reconstruction
Background Acellular dermal matrix (ADM) may improve outcomes in implant-based breast
reconstruction (IBBR). The aim of this study was critically to appraise and evaluate the …
reconstruction (IBBR). The aim of this study was critically to appraise and evaluate the …
The challenge of equipoise in trials with a surgical and non-surgical comparison: a qualitative synthesis using meta-ethnography
Background Randomised controlled trials in surgery can be a challenge to design and
conduct, especially when including a non-surgical comparison. As few as half of initiated …
conduct, especially when including a non-surgical comparison. As few as half of initiated …
A review of patient and carer participation and the use of qualitative research in the development of core outcome sets
Background To be meaningful, a core outcome set (COS) should be relevant to all
stakeholders including patients and carers. This review aimed to explore the methods by …
stakeholders including patients and carers. This review aimed to explore the methods by …
Exploring qualitative methods reported in registered trials and their yields (EQUITY): systematic review
C Clement, SL Edwards, F Rapport, IT Russell… - Trials, 2018 - Springer
Background The value of qualitative methods within trials is widely recognised, but their full
potential is not being realised. There are also issues with the visibility, recognition and …
potential is not being realised. There are also issues with the visibility, recognition and …
Challenges to and facilitators of recruitment to an Alzheimer's disease clinical trial: a qualitative interview study
C Clement, LE Selman, PG Kehoe… - Journal of …, 2019 - content.iospress.com
Background: Low participation in clinical trials is a major challenge to advancing clinical
Alzheimer's disease (AD) research and care. Factors influencing recruitment to AD trials are …
Alzheimer's disease (AD) research and care. Factors influencing recruitment to AD trials are …