Epidemiology of mild traumatic brain injury and neurodegenerative disease

RC Gardner, K Yaffe - Molecular and Cellular Neuroscience, 2015 - Elsevier
Every year an estimated 42 million people worldwide suffer a mild traumatic brain injury
(MTBI) or concussion. More severe traumatic brain injury (TBI) is a well-established risk …

Translational research in traumatic brain injury

D Laskowitz, G Grant - 2016 - books.google.com
Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Association of mild traumatic brain injury with and without loss of consciousness with dementia in US military veterans

DE Barnes, AL Byers, RC Gardner, KH Seal… - JAMA …, 2018 - jamanetwork.com
Importance Traumatic brain injury (TBI) is common in both veteran and civilian populations.
Prior studies have linked moderate and severe TBI with increased dementia risk, but the …

Risk of posttraumatic stress disorder and major depression in civilian patients after mild traumatic brain injury: a TRACK-TBI study

MB Stein, S Jain, JT Giacino, H Levin, S Dikmen… - JAMA …, 2019 - jamanetwork.com
Importance Traumatic brain injury (TBI) has been associated with adverse mental health
outcomes, such as posttraumatic stress disorder (PTSD) and major depressive disorder …

Memantine inhibits cortical spreading depolarization and improves neurovascular function following repetitive traumatic brain injury

MA MacLean, JH Muradov, R Greene… - Science …, 2023 - science.org
Cortical spreading depolarization (CSD) is a promising target for neuroprotective therapy in
traumatic brain injury (TBI). We explored the effect of NMDA receptor antagonism on …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Early clinical predictors of 5-year outcome after concussive blast traumatic brain injury

CL Mac Donald, J Barber, M Jordan… - JAMA …, 2017 - jamanetwork.com
Importance The long-term clinical effects of wartime traumatic brain injuries (TBIs), most of
which are mild, remain incompletely described. Current medical disability cost estimates …

A systematic review and meta-analysis on PTSD following TBI among military/veteran and civilian populations

A Loignon, MC Ouellet, G Belleville - The Journal of Head Trauma …, 2020 - journals.lww.com
Objectives: To determine whether persons with traumatic brain injury (TBI) are at greater risk
of developing posttraumatic stress disorder (PTSD) than other trauma-exposed populations …

Prospective longitudinal evaluation of the effect of deployment-acquired traumatic brain injury on posttraumatic stress and related disorders: results from the Army …

MB Stein, RC Kessler, SG Heeringa… - American Journal of …, 2015 - Am Psychiatric Assoc
Objective: Traumatic brain injury (TBI) is increasingly recognized as a risk factor for
deleterious mental health and functional outcomes. The purpose of this study was to …

Preinjury resilience and mood as predictors of early outcome following mild traumatic brain injury

SR McCauley, EA Wilde, ER Miller, ML Frisby… - Journal of …, 2013 - liebertpub.com
There is significant heterogeneity in outcomes following mild traumatic brain injury (mTBI).
While several host factors (age, gender, and preinjury psychiatric history) have been …