Evolution of mitochondrial gene content: gene loss and transfer to the nucleus

KL Adams, JD Palmer - Molecular phylogenetics and evolution, 2003 - Elsevier
Mitochondrial gene content is highly variable across extant eukaryotes. The number of
mitochondrial protein genes varies from 3 to 67, while tRNA gene content varies from 0 to …

Why do we still have a maternally inherited mitochondrial DNA? Insights from evolutionary medicine

DC Wallace - Annu. Rev. Biochem., 2007 - annualreviews.org
The human cell is a symbiosis of two life forms, the nucleus-cytosol and the mitochondrion.
The nucleus-cytosol emphasizes structure and its genes are Mendelian, whereas the …

Many Parallel Losses of infA from Chloroplast DNA during Angiosperm Evolution with Multiple Independent Transfers to the Nucleus

RS Millen, RG Olmstead, KL Adams, JD Palmer… - The Plant …, 2001 - academic.oup.com
We used DNA sequencing and gel blot surveys to assess the integrity of the chloroplast
gene infA, which codes for translation initiation factor 1, in> 300 diverse angiosperms …

Mitochondria of protists

MW Gray, BF Lang, G Burger - Annu. Rev. Genet., 2004 - annualreviews.org
▪ Abstract Over the past several decades, our knowledge of the origin and evolution of
mitochondria has been greatly advanced by determination of complete mitochondrial …

Pattern of organization of human mitochondrial pseudogenes in the nuclear genome

M Woischnik, CT Moraes - Genome research, 2002 - genome.cshlp.org
Mitochondrial pseudogenes in the human nuclear genome have been previously described,
mostly as a source of artifacts during the analysis of the mitochondrial genome. With the …

[HTML][HTML] Mitochondrial genomes revisited: why do different lineages retain different genes?

A Butenko, J Lukeš, D Speijer, JG Wideman - BMC biology, 2024 - Springer
The mitochondria contain their own genome derived from an alphaproteobacterial
endosymbiont. From thousands of protein-coding genes originally encoded by their …

[HTML][HTML] Cytochrome c oxidase: evolution of control via nuclear subunit addition

D Pierron, DE Wildman, M Hüttemann… - … et Biophysica Acta (BBA …, 2012 - Elsevier
According to theory, present eukaryotic cells originated from a beneficial association
between two free-living cells. Due to this endosymbiotic event the pre-eukaryotic cell gained …

Molecular Map of the Chlamydomonas reinhardtii Nuclear Genome

P Kathir, M LaVoie, WJ Brazelton, NA Haas… - Eukaryotic …, 2003 - Am Soc Microbiol
We have prepared a molecular map of the Chlamydomonas reinhardtii genome anchored to
the genetic map. The map consists of 264 markers, including sequence-tagged sites (STS) …

Allotopic expression of mitochondrial-encoded genes in mammals: achieved goal, undemonstrated mechanism or impossible task?

E Perales-Clemente, P Fernandez-Silva… - Nucleic acids …, 2011 - academic.oup.com
Mitochondrial-DNA diseases have no effective treatments. Allotopic expression—synthesis
of a wild-type version of the mutated protein in the nuclear-cytosolic compartment and its …

Limitations of allotopic expression of mitochondrial genes in mammalian cells

J Oca-Cossio, L Kenyon, H Hao, CT Moraes - Genetics, 2003 - academic.oup.com
The possibility of expressing mitochondrial DNA-coded genes in the nuclear-cytoplasmic
compartment provides an attractive system for genetic treatment of mitochondrial disorders …