Evolution of mitochondrial gene content: gene loss and transfer to the nucleus
Mitochondrial gene content is highly variable across extant eukaryotes. The number of
mitochondrial protein genes varies from 3 to 67, while tRNA gene content varies from 0 to …
mitochondrial protein genes varies from 3 to 67, while tRNA gene content varies from 0 to …
Why do we still have a maternally inherited mitochondrial DNA? Insights from evolutionary medicine
DC Wallace - Annu. Rev. Biochem., 2007 - annualreviews.org
The human cell is a symbiosis of two life forms, the nucleus-cytosol and the mitochondrion.
The nucleus-cytosol emphasizes structure and its genes are Mendelian, whereas the …
The nucleus-cytosol emphasizes structure and its genes are Mendelian, whereas the …
Many Parallel Losses of infA from Chloroplast DNA during Angiosperm Evolution with Multiple Independent Transfers to the Nucleus
We used DNA sequencing and gel blot surveys to assess the integrity of the chloroplast
gene infA, which codes for translation initiation factor 1, in> 300 diverse angiosperms …
gene infA, which codes for translation initiation factor 1, in> 300 diverse angiosperms …
Pattern of organization of human mitochondrial pseudogenes in the nuclear genome
M Woischnik, CT Moraes - Genome research, 2002 - genome.cshlp.org
Mitochondrial pseudogenes in the human nuclear genome have been previously described,
mostly as a source of artifacts during the analysis of the mitochondrial genome. With the …
mostly as a source of artifacts during the analysis of the mitochondrial genome. With the …
[HTML][HTML] Mitochondrial genomes revisited: why do different lineages retain different genes?
The mitochondria contain their own genome derived from an alphaproteobacterial
endosymbiont. From thousands of protein-coding genes originally encoded by their …
endosymbiont. From thousands of protein-coding genes originally encoded by their …
[HTML][HTML] Cytochrome c oxidase: evolution of control via nuclear subunit addition
D Pierron, DE Wildman, M Hüttemann… - … et Biophysica Acta (BBA …, 2012 - Elsevier
According to theory, present eukaryotic cells originated from a beneficial association
between two free-living cells. Due to this endosymbiotic event the pre-eukaryotic cell gained …
between two free-living cells. Due to this endosymbiotic event the pre-eukaryotic cell gained …
Molecular Map of the Chlamydomonas reinhardtii Nuclear Genome
P Kathir, M LaVoie, WJ Brazelton, NA Haas… - Eukaryotic …, 2003 - Am Soc Microbiol
We have prepared a molecular map of the Chlamydomonas reinhardtii genome anchored to
the genetic map. The map consists of 264 markers, including sequence-tagged sites (STS) …
the genetic map. The map consists of 264 markers, including sequence-tagged sites (STS) …
Allotopic expression of mitochondrial-encoded genes in mammals: achieved goal, undemonstrated mechanism or impossible task?
E Perales-Clemente, P Fernandez-Silva… - Nucleic acids …, 2011 - academic.oup.com
Mitochondrial-DNA diseases have no effective treatments. Allotopic expression—synthesis
of a wild-type version of the mutated protein in the nuclear-cytosolic compartment and its …
of a wild-type version of the mutated protein in the nuclear-cytosolic compartment and its …
Limitations of allotopic expression of mitochondrial genes in mammalian cells
The possibility of expressing mitochondrial DNA-coded genes in the nuclear-cytoplasmic
compartment provides an attractive system for genetic treatment of mitochondrial disorders …
compartment provides an attractive system for genetic treatment of mitochondrial disorders …