Detecting the near infrared autofluorescence of the human parathyroid: hype or opportunity?

CC Solórzano, G Thomas, N Baregamian… - Annals of …, 2020 - journals.lww.com
Objective: With the recent approval of 2 NIRAF-based devices for label-free identification of
PG by the Food and Drug Administration, it becomes crucial to educate the surgical …

[HTML][HTML] Optical spectroscopy for in vivo medical diagnosis—a review of the state of the art and future perspectives

JA Kim, DJ Wales, GZ Yang - Progress in Biomedical …, 2020 - iopscience.iop.org
When light is incident to a biological tissue surface, combinations of optical processes occur,
such as reflection, absorption, elastic and non-elastic scattering, and fluorescence. Analysis …

Current state of intraoperative use of near infrared fluorescence for parathyroid identification and preservation

CC Solórzano, G Thomas, E Berber, TS Wang… - Surgery, 2021 - Elsevier
Background Finding and preserving normal parathyroid glands or localizing and removing
diseased parathyroid glands are crucial steps to successful thyroid and parathyroid …

[HTML][HTML] Near-infrared autofluorescence in thyroid and parathyroid surgery

AN Di Marco, FF Palazzo - Gland surgery, 2020 - ncbi.nlm.nih.gov
Contrast-free autofluorescence (AF) of the parathyroid glands (PTGs) and thyroid tissue
occurs in the near-infrared (NIR) spectrum on excitation by light in the upper range of the …

[HTML][HTML] Fluorescence image-guided surgery for thyroid cancer: utility for preventing hypoparathyroidism

MS Demarchi, B Seeliger, JC Lifante, PF Alesina… - Cancers, 2021 - mdpi.com
Simple Summary The most frequent post-operative complication in thyroid surgery is
hypoparathyroidism leading to temporary or definitive low blood calcium levels. This …

Intraoperative identification of thyroid and parathyroid tissues during human endocrine surgery using the MasSpec pen

RJ DeHoog, ME King, MF Keating, J Zhang… - JAMA …, 2023 - jamanetwork.com
Importance Intraoperative identification of tissues through gross inspection during thyroid
and parathyroid surgery is challenging yet essential for preserving healthy tissue and …

Does the use of probe-based near-infrared autofluorescence parathyroid detection benefit parathyroidectomy?: A randomized single-center clinical trial

CM Kiernan, G Thomas, A Patel, R Fan, F Ye… - Annals of …, 2023 - journals.lww.com
Objective: To evaluate the benefits of probe-based near-infrared autofluorescence (NIRAF)
parathyroid identification during parathyroidectomy. Background: Intraoperative parathyroid …

Intraoperative uses of near-infrared fluorescence spectroscopy in pediatric surgery: A systematic review

H Alghoul, F Al Farajat, O Alser, AR Snyr… - Journal of Pediatric …, 2022 - Elsevier
Background The application of near infrared spectroscopy (NIRS) imaging in surgery is
growing. This study aimed to systematically review the literature to summarize the …

Light-triggered selective ROS-dependent autophagy by bioactive nanoliposomes for efficient cancer theranostics

T Appidi, DB Pemmaraju, RA Khan, SB Alvi… - Nanoscale, 2020 - pubs.rsc.org
Light-responsive nanoliposomes are being reported to induce cancer cell death through
heat and reactive oxygen species (ROS). Nanoliposomes (CIR NLPs) encapsulating a near …

Autofluorescence pattern of parathyroid adenomas

MS Demarchi, W Karenovics, B Bédat, C De Vito… - BJS open, 2021 - academic.oup.com
Background Primary hyperparathyroidism (pHPT) is a common endocrine pathology, and it
is due to a single parathyroid adenoma in 80–85 per cent of patients. Near-infrared …