Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment

ME Ertunc, GS Hotamisligil - Journal of lipid research, 2016 - ASBMB
Lipids encompass a wide variety of molecules such as fatty acids, sterols, phospholipids,
and triglycerides. These molecules represent a highly efficient energy resource and can act …

Quantitative proton MR techniques for measuring fat

HH Hu, HE Kan - NMR in biomedicine, 2013 - Wiley Online Library
Accurate, precise and reliable techniques for the quantification of body and organ fat
distributions are important tools in physiology research. They are critically needed in studies …

Melatonin increases brown adipose tissue mass and function in Zücker diabetic fatty rats: implications for obesity control

G Fernández Vázquez, RJ Reiter… - Journal of pineal …, 2018 - Wiley Online Library
Melatonin limits obesity in rodents without affecting food intake and activity, suggesting a
thermogenic effect. Previously we demonstrated that melatonin browns subcutaneous fat in …

Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice

L Zhou, SY Park, L Xu, X Xia, J Ye, L Su… - Nature …, 2015 - nature.com
Fsp27 is a lipid droplet-associated protein almost exclusively expressed in adipocytes
where it facilitates unilocular lipid droplet formation. In mice, Fsp27 deficiency is associated …

Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation

B Renvoisé, B Malone, M Falgairolle… - Human molecular …, 2016 - academic.oup.com
Hereditary spastic paraplegias (HSPs; SPG1-76 plus others) are length-dependent
disorders affecting long corticospinal axons, and the most common autosomal dominant …

Melatonin reduces obesity and restores adipokine patterns and metabolism in obese (ob/ob) mice

G Favero, A Stacchiotti, S Castrezzati, F Bonomini… - Nutrition Research, 2015 - Elsevier
The increasing incidence of obesity, leading to metabolic complications, is now recognized
as a major public health problem. The adipocytes are not merely energy-storing cells, but …

[HTML][HTML] Role of adipose tissue in methionine–choline-deficient model of non-alcoholic steatohepatitis (NASH)

P Jha, A Knopf, H Koefeler, M Mueller… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Abstract Methionine–choline-deficient (MCD) diet is a widely used dietary model of non-
alcoholic steatohepatitis (NASH) in rodents. However, the contribution of adipose tissue to …

Molecular imaging of brown adipose tissue in health and disease

M Bauwens, R Wierts, B Van Royen, J Bucerius… - European journal of …, 2014 - Springer
Purpose Brown adipose tissue (BAT) has transformed from an interfering tissue in
oncological 18 F-fluorodeoxyglucose (FDG) positron emission tomography (PET) to an …

Brown adipose tissue quantification in human neonates using water-fat separated MRI

JM Rasmussen, S Entringer, A Nguyen, TGM van Erp… - PloS one, 2013 - journals.plos.org
There is a major resurgence of interest in brown adipose tissue (BAT) biology, particularly
regarding its determinants and consequences in newborns and infants. Reliable methods …

Irisin induces white adipose tissue browning in mice as assessed by magnetic resonance imaging

Y Chen, J Ding, Y Zhao, S Ju, H Mao… - … Biology and Medicine, 2021 - journals.sagepub.com
This study aimed to track and evaluate the effect of low-dose irisin on the browning of white
adipose tissue (WAT) in mice using magnetic resonance imaging (MRI) noninvasively in …