Functional analysis of large gene lists, derived in most cases from emerging high-throughput
genomic, proteomic and bioinformatics scanning approaches, is still a challenging and …

Since its first release in 2007, GeneCodis has become a valuable tool to functionally
interpret results from experimental techniques in genomics. This web-based application …

In atherosclerotic arteries, blood monocytes differentiate to macrophages in the presence of
growth factors, such as macrophage colony-stimulation factor (M-CSF), and chemokines …

The apical junctional complex (AJC), composed of tight and adherens junctions, maintains
epithelial barrier function. Since cigarette smoking and chronic obstructive pulmonary …

The mechanistic basis for how genetic variants cause differences in phenotypic traits is often
elusive. We identified a quantitative trait locus in Caenorhabditis elegans that affects three …

Despite its wide usage in biological databases and applications, the role of the gene
ontology (GO) in network analysis is usually limited to functional annotation of genes or …

RNA silencing is a highly conserved pathway in the network of interconnected defense
responses that are activated during viral infection. As a counter-defense, many plant viruses …

BioProfiling. de provides a comprehensive analytical toolkit for the interpretation
gene/protein lists. As input, BioProfiling. de accepts a gene/protein list. As output, in one …

Subjective methods have been reported to adapt a general-purpose ontology for a specific
application. For example, Gene Ontology (GO) Slim was created from GO to generate a …

As the amount of genome information increases rapidly, there is a correspondingly greater
need for methods that provide accurate and automated annotation of gene function. For …