Asthma and obesity are prevalent disorders, each with a significant public health impact,
and a large and growing body of literature suggests an association between the two. The …

The human β-adrenoceptor is a member of the seven-transmembrane family of receptors,
encoded by a gene on chromosome 5. β-Adrenoceptors have been classified into β1, β2 …

Rationale: In patients with community-acquired pneumonia, guidelines recommend
antibiotic treatment for 7 to 21 d. Procalcitonin is elevated in bacterial infections, and its …

The beta2-adrenergic receptor (beta2AR) agonists are the most widely used agents in the
treatment of asthma, but the genetic determinants of responsiveness to these agents are …

Inhaled β-adrenergic agonists are the most commonly used medications for the treatment of
asthma although there is evidence that regular use may produce adverse effects in some …

Airway hyperresponsiveness is a characteristic feature of asthma and consists of an
increased sensitivity of the airways to an inhaled constrictor agonist, a steeper slope of the …

Asthma is a complex clinical syndrome with multiple genetic and enviromental factors
contributing to its phenotypic expression. This aetiological heterogeneity adds to the …

Objective: To investigate the influence of weight reduction on obese patients with asthma.
Design: Open study, two randomised parallel groups. Setting: Private outpatients centre …

BACKGROUND Polymorphisms of the β2 adrenoceptor influence receptor function in vitro
and asthma phenotypes in vivo. However, their importance in determining responses to …

Adrenergic receptors are expressed on virtually every cell type in the body and are the
receptors for epinephrine and norepinephrine within the sympathetic nervous system. They …