Lipid droplets are storage organelles at the centre of lipid and energy homeostasis. They
have a unique architecture consisting of a hydrophobic core of neutral lipids, which is …

Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …

The genetic circuits that allow cancer cells to evade destruction by the host immune system
remain poorly understood,–. Here, to identify a phenotypically robust core set of genes and …

Lipid droplets (LDs) are found in all cells and play critical roles in lipid metabolism. De novo
LD biogenesis occurs in the endoplasmic reticulum (ER) but is not well understood. We …

Our knowledge of inter-organellar communication has grown exponentially in recent years.
This review focuses on the interactions that cytoplasmic lipid droplets have with other …

Lipids are essential components for life. Their various structural and physical properties
influence diverse cellular processes and, thereby, human health. Lipids are not genetically …

Lipid droplets (LDs) are organelles that compartmentalize nonbilayer-forming lipids in the
aqueous cytoplasm of cells. They are ubiquitous in most organisms, including in animals …

Intracellular lipid droplets are utilized for lipid storage and metabolism in organisms as
evolutionarily diverse as animals, fungi, plants, bacteria, and archaea. These lipid droplets …

Obesity has reached epidemic proportions, leading to severe associated pathologies such
as insulin resistance, cardiovascular disease, cancer and type 2 diabetes. Adipose tissue …

Understanding organelle biogenesis is a central focus of cell biology. Whereas some are
generated from existing organelles, others can be generated de novo. Most de novo …