The nucleus accumbens (NAc), a central component of the brain's reward circuitry, has been
implicated in a wide range of behaviors and emotional states. Emerging evidence, primarily …

Abstract MDMA (3, 4-methylendioxymethamphetamine), also known as Ecstasy, is a
stimulant drug recreationally used by young adults usually in dance clubs and raves. Acute …

Previous studies have demonstrated that social defeat stress increases the rewarding effects
of psychostimulant drugs such as cocaine and amphetamine. In the present study we …

The interaction between MDMA and Nicotine affects multiple brain centres and
neurotransmitter systems (serotonin, dopamine and glutamate) involved in motor …

Abstract Some 3, 4-methylenedioxymethamphetamine (MDMA) users become dependent as
a result of chronic consumption. A greater understanding of the neurobiological basis of the …

Exposure to social defeat stress increases the rewarding effects of psychostimulants in
animal models, but its effect on 3, 4-methylenedioxymethylamphetamine (MDMA) reward …

Rationale The synthetic phenethylamines are recreational drugs known to produce
psychostimulant effects. However, their abuse potential has not been widely studied …

MDMA is a promising adjunct to psychotherapy and has well-known abuse liability, although
less than other amphetamine analogs. While the reinforcing dopamine (DA)-releasing …

In recent years, studies with animal models of reward, such as the intracranial self-
stimulation, self-administration, and conditioned place preference paradigms, have …

Although the consumption of cocaine is frequent in young users of MDMA (3, 4-
methylenedioxymethamphetamine), the influence of exposure to cocaine on the rewarding …