DNA methylation and chromatin–unraveling the tangled web
KD Robertson - Oncogene, 2002 - nature.com
Methylation of cytosines within the CpG dinucleotide by DNA methyltransferases is involved
in regulating transcription and chromatin structure, controlling the spread of parasitic …
in regulating transcription and chromatin structure, controlling the spread of parasitic …
The ICF syndrome, a DNA methyltransferase 3B deficiency and immunodeficiency disease
M Ehrlich - Clinical immunology, 2003 - Elsevier
Only one human disease that involves Mendelian inheritance of immunodeficiency and
aberrant DNA methylation has been identified. This is a rare chromosome breakage disease …
aberrant DNA methylation has been identified. This is a rare chromosome breakage disease …
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
The recessive autosomal disorder known as ICF syndrome,,(for immunodeficiency,
centromere instability and facial anomalies; Mendelian Inheritance in Man number 242860) …
centromere instability and facial anomalies; Mendelian Inheritance in Man number 242860) …
The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome
RS Hansen, C Wijmenga, P Luo… - Proceedings of the …, 1999 - National Acad Sciences
DNA methylation is an important regulator of genetic information in species ranging from
bacteria to humans. DNA methylation appears to be critical for mammalian development …
bacteria to humans. DNA methylation appears to be critical for mammalian development …
Cytosine methylation and mammalian development
Programmed methylation and demethylation of regulatory sequences has been proposed to
play a central role in vertebrate development. We report here that the methylation status of …
play a central role in vertebrate development. We report here that the methylation status of …
Prenatal synthetic glucocorticoid treatment changes DNA methylation states in male organ systems: multigenerational effects
A Crudo, S Petropoulos, VG Moisiadis, M Iqbal… - …, 2012 - academic.oup.com
Prenatal synthetic glucocorticoids (sGC) are administered to pregnant women at risk of
delivering preterm, approximately 10% of all pregnancies. Animal studies have …
delivering preterm, approximately 10% of all pregnancies. Animal studies have …
Heterogeneous clinical presentation in ICF syndrome: correlation with underlying gene defects
CMR Weemaes, MJ Van Tol, J Wang… - European Journal of …, 2013 - nature.com
Immunodeficiency with centromeric instability and facial anomalies (ICF) syndrome is a
primary immunodeficiency, predominantly characterized by agammaglobulinemia or …
primary immunodeficiency, predominantly characterized by agammaglobulinemia or …
Peripheral nerve injury is associated with chronic, reversible changes in global DNA methylation in the mouse prefrontal cortex
M Tajerian, S Alvarado, M Millecamps, P Vachon… - PloS one, 2013 - journals.plos.org
Changes in brain structure and cortical function are associated with many chronic pain
conditions including low back pain and fibromyalgia. The magnitude of these changes …
conditions including low back pain and fibromyalgia. The magnitude of these changes …
[HTML][HTML] DNA methylation and histone deacetylation in the control of gene expression: basic biochemistry to human development and disease
A El-Osta, AP Wolffe - Gene expression, 2000 - ncbi.nlm.nih.gov
DNA methylation is a major determinant in the epigenetic silencing of genes. The
mechanisms underlying the targeting of DNA methylation and the subsequent repression of …
mechanisms underlying the targeting of DNA methylation and the subsequent repression of …
DNA demethylation and pericentromeric rearrangements of chromosome 1
W Ji, R Hernandez, XY Zhang, G Qu, A Frady… - Mutation Research …, 1997 - Elsevier
Rearrangements in the vicinity of the centromere of chromosome 1 are over-represented in
many types of human cancer and are a characteristic feature of a rare genetic disease called …
many types of human cancer and are a characteristic feature of a rare genetic disease called …