[HTML][HTML] Hepatokines and adipokines in NASH-related hepatocellular carcinoma
O Kucukoglu, JP Sowa, GD Mazzolini, WK Syn… - Journal of …, 2021 - Elsevier
The incidence of hepatocellular carcinoma (HCC) is increasing in industrialized societies;
this is likely secondary to the increasing burden of non-alcoholic fatty liver disease (NAFLD) …
this is likely secondary to the increasing burden of non-alcoholic fatty liver disease (NAFLD) …
Targeting nuclear receptors for the treatment of fatty liver disease
N Tanaka, T Aoyama, S Kimura, FJ Gonzalez - Pharmacology & …, 2017 - Elsevier
Ligand-activated nuclear receptors, including peroxisome proliferator-activated receptor
alpha (PPARα), pregnane X receptor, and constitutive androstane receptor, were first …
alpha (PPARα), pregnane X receptor, and constitutive androstane receptor, were first …
[HTML][HTML] Role of diet and gut microbiota on colorectal cancer immunomodulation
CV De Almeida, MR de Camargo, E Russo… - World journal of …, 2019 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers, and it is
characterized by genetic and epigenetic alterations, as well as by inflammatory cell …
characterized by genetic and epigenetic alterations, as well as by inflammatory cell …
[HTML][HTML] Current status, problems, and perspectives of non-alcoholic fatty liver disease research
N Tanaka, T Kimura, N Fujimori, T Nagaya… - World journal of …, 2019 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is a major chronic liver disease that can lead to
liver cirrhosis, liver cancer, and ultimately death. NAFLD is pathologically classified as non …
liver cirrhosis, liver cancer, and ultimately death. NAFLD is pathologically classified as non …
[HTML][HTML] Mild drinking habit is a risk factor for hepatocarcinogenesis in non-alcoholic fatty liver disease with advanced fibrosis
T Kimura, N Tanaka, N Fujimori, A Sugiura… - World journal of …, 2018 - ncbi.nlm.nih.gov
AIM The impact of mild drinking habit (less than 20 g/d of ethanol) on the clinical course of
non-alcoholic fatty liver disease (NAFLD) has not been determined. We examined the …
non-alcoholic fatty liver disease (NAFLD) has not been determined. We examined the …
Serum thrombospondin 2 is a novel predictor for the severity in the patients with NAFLD
T Kimura, N Tanaka, N Fujimori, T Yamazaki… - Liver …, 2021 - Wiley Online Library
Aim Thrombospondins are a family of multidomain and secretory glycoproteins. Among
them, thrombospondin 2 (TSP2) encoded by TSP2 gene has been reported to be involved in …
them, thrombospondin 2 (TSP2) encoded by TSP2 gene has been reported to be involved in …
Impact of dietary fat on the progression of liver fibrosis: lessons from animal and cell studies
F Jia, X Hu, T Kimura, N Tanaka - International journal of molecular …, 2021 - mdpi.com
Previous studies have revealed that a high-fat diet is one of the key contributors to the
progression of liver fibrosis, and increasing studies are devoted to analyzing the different …
progression of liver fibrosis, and increasing studies are devoted to analyzing the different …
[PDF][PDF] Role of farnesoid X receptor and bile acids in hepatic tumor development
S Takahashi, N Tanaka, T Fukami, C Xie… - Hepatology …, 2018 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a leading cause of cancer deaths worldwide, and an
association between altered bile acid (BA) metabolism, down‐regulation of farnesoid X …
association between altered bile acid (BA) metabolism, down‐regulation of farnesoid X …
Role of G protein-coupled receptors in hepatic stellate cells and approaches to anti-fibrotic treatment of non-alcoholic fatty liver disease
The prevalence of non-alcoholic fatty liver disease (NAFLD) is globally increasing. Gaining
control over disease-related events in non-alcoholic steatohepatitis (NASH), an advanced …
control over disease-related events in non-alcoholic steatohepatitis (NASH), an advanced …
Associations between abdominal obesity indices and pathological features of non‐alcoholic fatty liver disease: Chinese visceral adiposity index
R Li, J Liu, P Han, R Shi, L Zhao… - … of Gastroenterology and …, 2023 - Wiley Online Library
Abstract Background and Aim Many abdominal obesity indices such as waist circumference
(WC), lipid accumulation product (LAP), visceral obesity index (VAI), and Chinese VAI …
(WC), lipid accumulation product (LAP), visceral obesity index (VAI), and Chinese VAI …