Recent developments in biological activities of chalcones: A mini review
Chalcones represent key structural motif in the plethora of biologically active molecules
including synthetic and natural products. Synthetic manipulations of chalcones or their …
including synthetic and natural products. Synthetic manipulations of chalcones or their …
Anti-cancer chalcones: Structural and molecular target perspectives
Abstract Chalcone or (E)-1, 3-diphenyl-2-propene-1-one scaffold remained a fascination
among researchers in the 21st century due to its simple chemistry, ease of synthesis and a …
among researchers in the 21st century due to its simple chemistry, ease of synthesis and a …
Chalcone: a promising bioactive scaffold in medicinal chemistry
G Rajendran, D Bhanu, B Aruchamy, P Ramani… - Pharmaceuticals, 2022 - mdpi.com
Chalcones are a class of privileged scaffolds with high medicinal significance due to the
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …
The importance of indole and azaindole scaffold in the development of antitumor agents
Y Han, W Dong, Q Guo, X Li, L Huang - European journal of medicinal …, 2020 - Elsevier
With some indoles and azaindoles being successfully developed as anticancer drugs, the
design and synthesis of indole and azaindole derivatives with remarkable antitumor activity …
design and synthesis of indole and azaindole derivatives with remarkable antitumor activity …
Exploring pharmacological significance of chalcone scaffold: a review
NK Sahu, SS Balbhadra… - Current medicinal …, 2012 - ingentaconnect.com
Chalcones (1, 3-diaryl-2-propen-1-ones) and their heterocyclic analogues, belong to the
flavonoid family, which possess a number of interesting biological properties such as …
flavonoid family, which possess a number of interesting biological properties such as …
Synthesis and pharmacological properties of chalcones: a review
SL Gaonkar, UN Vignesh - Research on chemical intermediates, 2017 - Springer
Chalcones and their analogs have been an area of great interest in recent years. Numerous
research papers have been published, and chalcones continue to show promise for new …
research papers have been published, and chalcones continue to show promise for new …
The role of phenolic compounds in the fight against cancer–a review
M Carocho, I CFR Ferreira - Anti-Cancer Agents in Medicinal …, 2013 - ingentaconnect.com
Cancer is a worldwide scourge; it's the leading cause of death in developed countries and is
increasing in developing countries. Mankind has been trying with effort to find better and …
increasing in developing countries. Mankind has been trying with effort to find better and …
Advances in chalcones with anticancer activities
C Karthikeyan, N SH Narayana Moorthy… - Recent patents on …, 2015 - ingentaconnect.com
Chalcones are naturally occurring compounds exhibiting broad spectrum biological
activities including anticancer activity through multiple mechanisms. Literature on anticancer …
activities including anticancer activity through multiple mechanisms. Literature on anticancer …
Chalcone hybrids as potential anticancer agents: Current development, mechanism of action, and structure‐activity relationship
F Gao, G Huang, J Xiao - Medicinal research reviews, 2020 - Wiley Online Library
The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …
agents have been the major challenges in the control and treatment of cancer, making an …
Synthesis of chalcones with anticancer activities
Several chalcones were synthesized and their in vitro cytotoxicity against various human cell
lines, including human breast adenocarcinoma cell line MCF-7, human lung …
lines, including human breast adenocarcinoma cell line MCF-7, human lung …