Chalcones represent key structural motif in the plethora of biologically active molecules
including synthetic and natural products. Synthetic manipulations of chalcones or their …

Abstract Chalcone or (E)-1, 3-diphenyl-2-propene-1-one scaffold remained a fascination
among researchers in the 21st century due to its simple chemistry, ease of synthesis and a …

Chalcones are a class of privileged scaffolds with high medicinal significance due to the
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …

With some indoles and azaindoles being successfully developed as anticancer drugs, the
design and synthesis of indole and azaindole derivatives with remarkable antitumor activity …

Chalcones (1, 3-diaryl-2-propen-1-ones) and their heterocyclic analogues, belong to the
flavonoid family, which possess a number of interesting biological properties such as …

Chalcones and their analogs have been an area of great interest in recent years. Numerous
research papers have been published, and chalcones continue to show promise for new …

Cancer is a worldwide scourge; it's the leading cause of death in developed countries and is
increasing in developing countries. Mankind has been trying with effort to find better and …

Chalcones are naturally occurring compounds exhibiting broad spectrum biological
activities including anticancer activity through multiple mechanisms. Literature on anticancer …

The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …

Several chalcones were synthesized and their in vitro cytotoxicity against various human cell
lines, including human breast adenocarcinoma cell line MCF-7, human lung …