Ag (i)-catalyzed asymmetric (2+ 4) annulation reaction of 5-alkenyl thiazolones: synthesis of enantioenriched spiro [cyclohexenamines-thiazolones]

K Choudhary, AS Deshpande, VK Singh - Chemical Communications, 2024 - pubs.rsc.org
The first metal-catalyzed (2+ 4) annulation of 5-alkenyl thiazolones and α, α-
dicyanoalkylidenes has been developed via vinylogous Michael/cyclization/isomerization …

Asymmetric Organocatalytic Diels–Alder Reaction of Olefinic Azlactones with Unsaturated Thiazolones: Access to Spirocyclohexenone Thiazolone Skeletons

ZA Khan, VK Singh - The Journal of Organic Chemistry, 2024 - ACS Publications
Chiral bifunctional thiourea-catalyzed Diels–Alder reaction between olefinic azlactones and
alkylidene thiazolone derivatives is reported here for the first time. The asymmetric Diels …

Analysis of pharmacokinetic profile and ecotoxicological character of cefepime and its photodegradation products

J Żandarek, P Żmudzki, D Obradović, S Lazović… - Chemosphere, 2024 - Elsevier
An important problem is the impact of photodegradation on product toxicity in biological
tests, which may be complex and context-dependent. Previous studies have described the …

[HTML][HTML] Synthesis of Carborane–Thiazole Conjugates as Tyrosinase and 11β-Hydroxysteroid Dehydrogenase Inhibitors: Antiproliferative Activity and Molecular …

B Donarska, J Cytarska, D Kołodziej-Sobczak… - Molecules, 2024 - mdpi.com
The presented study depicts the synthesis of 11 carborane–thiazole conjugates with
anticancer activity, as well as an evaluation of their biological activity as inhibitors of two …

Thiazole derivatives: prospectives and biological applications

U Fathy - Journal of Sulfur Chemistry, 2024 - Taylor & Francis
Thiazole derivatives have long been a hot topic in pharmaceutical research and remain
among the greatest active fields in heterocyclic chemistry. Thiazole derivatives, as one of the …

Glikokortykosteroidy-nowy cel w leczeniu zespołu metabolicznego

S Baumgart, D Kupczyk, R Studzińska - Farmacja Polska, 2024 - omega.umk.pl
Glucocorticoids are hormones belonging to the group of steroid hormones produced by the
adrenal cortex and are necessary for the proper maintenance of metabolic (including lipid …

Synthesis, characterization and biological activities of novel mononuclear nickel (II), copper (II) and chromium (III) complexes with N, N-dilaurylsubstituted thiazolidine …

MS Aksoy, A Yıldırım, AG Sarıkaya - 2024 - researchsquare.com
For the first time, a thiazolidine-4-one-5-acetic acid with two long hydrocarbon chains was
chosen as ligand and the corresponding metal complexes with Cr (III), Ni (II) and Cu (II) salts …

Evaluación bioinformática de metilfenilhidrazonas cristalinas y su potencial actividad farmacológica contra cáncer de tipo hormona-dependiente

M Hernández Aguilando - repositorioinstitucional.buap.mx
Abstract" En la presente investigación se utilizaron herramientas bioinformáticas para
analizar el potencial biológico de las moléculas derivadas de la metilfenilhidrazona frente a …