Cryopreservation of cells and biologics underpins all biomedical research from routine
sample storage to emerging cell-based therapies, as well as ensuring cell banks provide …

In nature, many biological organisms have developed the exceptional antifreezing ability to
survive in extremely cold environments. Inspired by the freeze resistance of these …

Cells and tissues are the foundation of translational medicine. At present, one of the main
technological obstacles is their preservation for long-term usage while maintaining …

Trehalose is a naturally occurring, nonreducing disaccharide that is widely used in the
biopharmaceutical, food, and cosmetic industries due to its stabilizing and cryoprotective …

Cryopreservation is a process used for the storage of mammalian cells at a very low
temperature, in a state of 'suspended animation.'Highly effective and safe macromolecular …

Background A medium containing dimethyl sulfoxide (DMSO)(10% v/v) is most widely used
for cell cryopreservation at–196° C. However, residual DMSO consistently raises concerns …

The random amphiphilic copolymers containing a large fraction (35–50 mol%) of
ureidopyrimidinone (UPy) that can dimerize using a quadruple hydrogen bonding were …

Cell cryopreservation is crucial for biomedicine, and the addition of cryoprotectants (CPAs)
to protect cells from cryoinjuries is essential at low temperatures. Trehalose (Tre) has been …

Polymers, especially charged polymers, are the key to a sustainable future, as they have the
capability to act as alternatives to plastics, reduce the impact of global warming, and offer …

Tissue engineering involves the transplantation of stem cell-laden hydrogels as synthetic
constructs to replace damaged tissues. However, their time-consuming fabrication …