Dipeptidyl-peptidase IV/CD26 (DPP IV) is a cell-surface protease belonging to the
prolyloligopeptidase family. It selectively removes the N-terminal dipeptide from peptides …

Proteases form one of the largest and more important groups of enzymes. They selectively
catalyze the hydrolysis of peptide bonds and can be divided into four major classes …

HIV‐1 encodes for the small basic protein Tat (86–101 residues) that drastically enhances
the efficiency of viral transcription. The mechanism enabling Tat nuclear import is not yet …

CD26 has proved interesting in the fields of immunology, endocrinology, cancer biology and
nutrition owing to its ubiquitous and unusual enzyme activity. This dipeptidyl …

CD26 is a widely distributed 110 kD cell‐surface glycoprotein with known dipeptidyl‐
peptidase IV (DPP‐IV) activity in its extracellular domain. This ectoenzyme is capable of …

The costimulatory properties of CD26 have been studied extensively and significant
progress has been made in unravelling the complex nature of this molecule. Here, we …

Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or
T-cell activation antigen CD26 (EC 3.4. 14.5.) is a serine exopeptidase belonging to the S9B …

Apoptosis (programmed cell death) of T lymphocytes has been proposed as a mechanism
which plays an important role in the pathogenesis of human immunodeficiency virus (HIV) …

Nearly 50% of HIV-infected individuals suffer from some form of HIV-associated
neurocognitive disorders (HAND). HIV-1 Tat (a key HIV t rans a ctivator of t ranscription) …

This review deals with the properties and functions of dipeptidyl peptidase IV (DPP IV, EC
3.4. 14.5). This membrane anchored ecto-protease has been identified as the leukocyte …