Ferlins are multiple-C2-domain proteins involved in Ca2+-triggered membrane dynamics
within the secretory, endocytic and lysosomal pathways. In bony vertebrates there are six …

Humans have six members of the ferlin protein family: dysferlin, myoferlin, otoferlin, fer1L4,
fer1L5, and fer1L6. These proteins share common features such as multiple Ca2+-binding …

Background: Pancreatic carcinoma (PC) is an aggressive malignancy that lacks strategies
for early detection. This study aimed to develop a coherent, high-throughput and non …

Furunculosis caused by Aeromonas salmonicida subsp. salmonicida is an epidemic disease
among salmonids, including rainbow trout (Oncorhynchus mykiss). However, the immune …

Exosomes are communication mediators participating in the intercellular exchange of
proteins, metabolites and nucleic acids. Recent studies have demonstrated that exosomes …

Myoferlin is a multiple C2-domain-containing protein that regulates membrane repair,
tyrosine kinase receptor function and endocytosis in myoblasts and endothelial cells …

Background Pancreatic cancer (PC) is the fourth leading cause of cancer death because of
its subtle clinical symptoms in the early stage. To discover particular serum metabolites as …

Ferlins are a family of transmembrane‐anchored vesicle fusion proteins uniquely
characterized by 5–7 tandem cytoplasmic C2 domains, Ca2+‐regulated phospholipid …

Pancreatic ductal adenocarcinoma is one of the most deadly forms of cancers with no
satisfactory treatment to date. Recent studies have identified myoferlin, a ferlin family …

BRAF mutations are associated with aggressive, less-differentiated and therapy-resistant
colorectal carcinoma. However, the underlying mechanisms for these correlations remain …