Prognostic genes of breast cancer identified by gene co-expression network analysis

J Tang, D Kong, Q Cui, K Wang, D Zhang… - Frontiers in …, 2018 - frontiersin.org
Breast cancer is one of the most common malignancies. The molecular mechanisms of its
pathogenesis are still to be investigated. The aim of this study was to identify the potential …

Multi-class and multi-scale models of complex biological phenomena

SY Jessica, N Bagheri - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Choice of modeling framework should account for experimental context and
data.•Accurate models offer biological insight and explain non-intuitive observations.•Multi …

Basal-like breast cancer: molecular profiles, clinical features and survival outcomes

HH Milioli, I Tishchenko, C Riveros, R Berretta… - BMC medical …, 2017 - Springer
Background Basal-like constitutes an important molecular subtype of breast cancer
characterised by an aggressive behaviour and a limited therapy response. The outcome of …

The cell cycle‐related genes RHAMM, AURKA, TPX2, PLK1, and PLK4 are associated with the poor prognosis of breast cancer patients

I Kahl, J Mense, C Finke, AL Boller… - Journal of Cellular …, 2022 - Wiley Online Library
Breast cancer is the third most common type of cancer diagnosed. Cell cycle is a complex
but highly organized and controlled process, in which normal cells sense mitogenic growth …

[PDF][PDF] RETRACTED ARTICLE: MiR-29a-5p inhibits proliferation and invasion and induces apoptosis in endometrial carcinoma via targeting TPX2

T Jiang, D Sui, D You, S Yao, L Zhang, Y Wang… - Cell Cycle, 2018 - Taylor & Francis
Statement of Retraction We, the Editors and Publisher of the journal Cell Cycle, have
retracted the following article: Tiechao Jiang, Dongming Sui, Dong You, Songmei Yao …

[HTML][HTML] Targeting TPX2 suppresses the tumorigenesis of hepatocellular carcinoma cells resulting in arrested mitotic phase progression and increased genomic …

CW Hsu, YC Chen, HH Su, GJ Huang, CW Shu… - Journal of …, 2017 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) remains one of the most difficult cancers to treat, with
chemotherapies being relatively ineffective. Therefore, a better knowledge of molecular …

Therapeutic targeting of the TPX2/TTK network in colorectal cancer

H Shaath, R Vishnubalaji, R Elango… - Cell Communication and …, 2023 - Springer
Background While the increased screening, changes in lifestyle, and recent advances in
treatment regimen have decreased colorectal cancer (CRC) mortality, metastatic disease …

[HTML][HTML] TPX2 promotes migration and invasion of human breast cancer cells

Y Yang, DP Li, N Shen, XC Yu, JB Li, Q Song… - Asian Pacific journal of …, 2015 - Elsevier
Objective To investigate the expression of targeting protein for Xenopus kinesin-like protein
2 (TPX2) in breast cancer tissue and to explore its role in proliferation, migration and …

bub1 as a potential oncogene and a prognostic biomarker for neuroblastoma

J Song, C Ni, X Dong, C Sheng, Y Qu, L Zhu - Frontiers in Oncology, 2022 - frontiersin.org
Background Neuroblastoma is the most common malignant extracranial tumor for children.
Molecular mechanisms underpinning the pathogenesis of this disease are yet to be fully …

An integrated genome-wide systems genetics screen for breast cancer metastasis susceptibility genes

L Bai, HH Yang, Y Hu, A Shukla, NH Ha, A Doran… - PLoS …, 2016 - journals.plos.org
Metastasis remains the primary cause of patient morbidity and mortality in solid tumors and
is due to the action of a large number of tumor-autonomous and non-autonomous factors …