Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China …

Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality.
Consequences vary from mild cognitive impairment to death and, no matter the severity of …

Microglia are the tissue-resident macrophages of the central nervous parenchyma. In
mammals, microglia are thought to originate from yolk sac precursors and posteriorly …

Long‐term neurological deficits after severe traumatic brain injury (TBI), including cognitive
dysfunction and emotional impairments, can significantly impair rehabilitation. Glial …

A harmonic brain–body communication is fundamental to individual wellbeing and is the
basis of human cognition and behavior. In the last 2 decades, the interaction between the …

Brain injuries are devastating conditions, representing a global cause of mortality and
morbidity, with no effective treatment to date. Increased evidence supports the role of …

This review outlined evidence that purinergic signaling is involved in the modulation of
blood-brain barrier (BBB) permeability. The functional and structural integrity of the BBB is …

Traumatic brain injury (TBI) is a heterogeneous condition, associated with diverse etiologies,
clinical presentations and degrees of severity, and may result in chronic neurobehavioral …

Background Severe traumatic brain injury (TBI) is associated with blood–brain barrier (BBB)
disruption and a subsequent neuroinflammatory process. We aimed to perform a multiplex …

Stroke disrupts the homeostatic balance within the brain and is associated with a significant
accumulation of necrotic cellular debris, fluid, and peripheral immune cells in the central …