[HTML][HTML] Ozone: a natural bioactive molecule with antioxidant property as potential new strategy in aging and in neurodegenerative disorders
C Scassellati, AC Galoforo, C Bonvicini… - Ageing Research …, 2020 - Elsevier
Abstract Systems medicine is founded on a mechanism-based approach and identifies in
this way specific therapeutic targets. This approach has been applied for the transcription …
this way specific therapeutic targets. This approach has been applied for the transcription …
Mitochondria-targeted senotherapeutic interventions
Healthy aging is the art of balancing a delicate scale. On one side of the scale, there are the
factors that make life difficult with aging, and on the other side are the products of human …
factors that make life difficult with aging, and on the other side are the products of human …
Melatonin, its metabolites and their interference with reactive nitrogen compounds
R Hardeland - Molecules, 2021 - mdpi.com
Melatonin and several of its metabolites are interfering with reactive nitrogen. With the notion
of prevailing melatonin formation in tissues that exceeds by far the quantities in blood …
of prevailing melatonin formation in tissues that exceeds by far the quantities in blood …
[PDF][PDF] The possibilities of using the effects of ozone therapy in neurology
J Masan, M Sramka, D Rabarova - Neuroendocrinol. Lett, 2021 - 3medgroup.com
OBJECTIVES: The beneficial effects of ozone therapy consist mainly of the promotion of
blood circulation: peripheral and central ischemia, immunomodulatory effect, energy boost …
blood circulation: peripheral and central ischemia, immunomodulatory effect, energy boost …
Dynamics of redox signaling in aging via autophagy, inflammation, and senescence
Review paper attempts to explain the dynamic aspects of redox signaling in aging through
autophagy, inflammation, and senescence. It begins with ROS source in the cell, then states …
autophagy, inflammation, and senescence. It begins with ROS source in the cell, then states …
Conserved age‐related increases in hippocampal PDE11A4 cause unexpected proteinopathies and cognitive decline of social associative memories
K Pilarzyk, L Porcher, WR Capell, SD Burbano… - Aging …, 2022 - Wiley Online Library
In humans, associative memories are more susceptible to age‐related cognitive decline
(ARCD) than are recognition memories. Reduced cAMP/cGMP signaling in the …
(ARCD) than are recognition memories. Reduced cAMP/cGMP signaling in the …
Molecular mechanism of caloric restriction mimetics-mediated neuroprotection of age-related neurodegenerative diseases: an emerging therapeutic approach
Aging-induced neurodegenerative diseases (NDs) are significantly increasing health
problem worldwide. It has been well documented that oxidative stress is one of the potential …
problem worldwide. It has been well documented that oxidative stress is one of the potential …
The absence of gastrointestinal redox dyshomeostasis in the brain-first rat model of Parkinson's disease induced by bilateral intrastriatal 6-hydroxydopamine
The gut-brain axis plays an important role in Parkinson's disease (PD) by acting as a route
for vagal propagation of aggregated α-synuclein in the gut-first endophenotype and as a …
for vagal propagation of aggregated α-synuclein in the gut-first endophenotype and as a …
[HTML][HTML] Effect of nacre extract from pearl oyster shells against behavioral and psychological symptoms of dementia in senescence-accelerated mouse P8 (SAMP8)
T Omachi, Y Hasegawa - Journal of Functional Foods, 2024 - Elsevier
Pearls have been used in traditional Chinese medicine for the treatment of myopia, epilepsy,
and palpitations. We previously demonstrated that the intraperitoneal administration of nacre …
and palpitations. We previously demonstrated that the intraperitoneal administration of nacre …