Impact of plant extracts on hepatic redox metabolism upon lead exposure: a systematic review of preclinical in vivo evidence
ALF Destro, P da Silva Mattosinhos, RD Novaes… - … Science and Pollution …, 2023 - Springer
The liver is a central target organ of heavy metals toxicity, and secondary metabolites of
several plant species are suggested to attenuate lead (Pb)-induced hepatotoxicity through …
several plant species are suggested to attenuate lead (Pb)-induced hepatotoxicity through …
Protective effects of sinapic acid against lead acetate-induced nephrotoxicity: a multi-biomarker approach
Lead acetate (PbAc) is one of the top five most dangerous toxic heavy metals, particularly
leading to kidney damage and posing serious health risks in both humans and animals …
leading to kidney damage and posing serious health risks in both humans and animals …
Ginkgo biloba supplement abates lead-induced endothelial and testicular dysfunction in Wistar rats via up-regulation of Bcl-2 protein expression, pituitary-testicular …
Background Apoptotic and oxido-inflammatory pathways have been found to be up-
regulated in lead acetate poisoning which has been associated to endothelial and testicular …
regulated in lead acetate poisoning which has been associated to endothelial and testicular …
[HTML][HTML] Inhibition of oxido-inflammatory and apoptotic pathway is involved in the protective effect of Ginkgo biloba supplement in cyclosporine-A induced vascular …
Abstract Background Cyclosporine (Cs-A), an immunosuppressant drug used to prevent
organ rejection in patients receiving organ transplants, has been linked to cardiovascular …
organ rejection in patients receiving organ transplants, has been linked to cardiovascular …
[HTML][HTML] Enhancements of Bcl-2/mTOR/ERK1/2 activities by antioxidant mechanisms confer cardioprotection on Ginkgo biloba supplement against isoprenaline …
Background Myocyte necrosis and apoptosis can be severely induced by acute adrenergic
stimulation due to the activation of several cell signalling pathways. However, uncertainty …
stimulation due to the activation of several cell signalling pathways. However, uncertainty …
Ginkgo biloba modulates ET-I/NO signalling in Lead Acetate induced rat model of endothelial dysfunction: Involvement of oxido-inflammatory mediators
This study investigated the modulatory effect of Ginkgo biloba extract on lead acetate-
induced endothelial dysfunction. Animals were administered GBE (50 mg/kg and 100 mg/kg …
induced endothelial dysfunction. Animals were administered GBE (50 mg/kg and 100 mg/kg …
Treatment with Ginkgo biloba supplement modulates oxidative disturbances, inflammation and vascular functions in oxygen deprived hypothyroid mice: Involvement …
A double‐hit biological alteration involving exposure to oxygen deprivation in hypothyroid
condition may exacerbate cellular oxidative and inflammatory disturbances comparative to a …
condition may exacerbate cellular oxidative and inflammatory disturbances comparative to a …
Terminalia catappa attenuates phenylhydrazine-induced anaemia and hepato-renal toxicity in male Wistar rat by boosting blood cells, modulation of lipoproteins and up …
E Umoren, JN Asiwe, IA Okon, A Levi Amangieka… - Biomarkers, 2023 - Taylor & Francis
Aim This study investigated the haematinic, antihyperlipidaemic, hepato-renal protective
effects of Terminalia catappa aqueous leaf extract on male Wistar rats exposed to …
effects of Terminalia catappa aqueous leaf extract on male Wistar rats exposed to …
[HTML][HTML] Pleiotropic attenuating effect of Ginkgo biloba against isoprenaline-induced myocardial infarction via improving Bcl-2/mTOR/ERK1/2/Na+, K+-ATPase …
Objective Myocardial infarction (MI) is linked to an imbalance in the supply and demand of
blood oxygen in the heart muscles. Beta-blockers and calcium antagonists are just two of the …
blood oxygen in the heart muscles. Beta-blockers and calcium antagonists are just two of the …
Sodium Metabisulfite‐Induced Hematotoxicity, Oxidative Stress, and Organ Damage Ameliorated by Standardized Ginkgo biloba in Mice
NW Wairimu, P Wairagu, KW Chepukosi… - Journal of …, 2023 - Wiley Online Library
Sodium metabisulfite (SMB) is a biocide and antioxidant agent generally used as a
preservative in food and beverage industries but can oxidize to harmful sulfite radicals. A …
preservative in food and beverage industries but can oxidize to harmful sulfite radicals. A …