Nanosponges for drug delivery and cancer therapy: Recent advances

S Iravani, RS Varma - Nanomaterials, 2022 - mdpi.com
Nanosponges with three-dimensional (3D) porous structures, narrow size distribution, and
high entrapment efficiency are widely engineered for cancer therapy and drug delivery …

Nanosponges as an emerging platform for cancer treatment and diagnosis

BHJ Gowda, MG Ahmed, MAA Almoyad… - Advanced Functional …, 2024 - Wiley Online Library
Nanosponges are unique sponge‐like carrier systems with numerous cavities and a mesh‐
like network throughout their surface. They are categorized into three types based on the …

A review of FDA approved drugs and their formulations for the treatment of breast cancer

M Chaurasia, R Singh, S Sur, SJS Flora - Frontiers in Pharmacology, 2023 - frontiersin.org
Breast cancer is one of the most diagnosed solid cancers globally. Extensive research has
been going on for decades to meet the challenges of treating solid tumors with selective …

Redox responsive polymeric micelles of gellan gum/abietic acid for targeted delivery of ribociclib

S Shirani, J Varshosaz, M Rostami, M Mirian - International Journal of …, 2022 - Elsevier
In most breast tumors level of glutathione reductase is much higher than in healthy tissues.
In the current study, a redox-glutathione sensitive micelle based on Abietic acid-Cystamine …

Ribociclib hybrid lipid–polymer nanoparticle preparation and characterization for cancer treatment

R Al-Shdefat, M Hailat, OY Alshogran, W Abu Dayyih… - Polymers, 2023 - mdpi.com
Ribociclib is a newly approved orally administered drug for breast cancer. This study aimed
to prepare, characterize, and evaluate hybrid lipid–polymer nanoparticles (PLNs) of …

[HTML][HTML] β-Cyclodextrin nanosponges for enhanced anti-melanoma potential of silymarin with functions of anti-oxidant, anti-inflammatory and anti-tyrosinase

P Dalal, R Rao - Results in Chemistry, 2023 - Elsevier
Overproduction of inflammatory and oxidative species has been identified as key
contributors for skin cancer progression. Silymarin (SLY), a natural flavonoid has …

[HTML][HTML] Optimized Ribociclib nanostructured lipid carrier for the amelioration of skin cancer: Inferences from ex-vivo skin permeation and dermatokinetic studies

MF Aldawsari, MA Kamal, MF Balaha, T Jawaid… - Saudi Pharmaceutical …, 2024 - Elsevier
Current research focuses on explicitly developing and evaluating nanostructured lipidic
carriers (NLCs) for the chemotherapeutic drug Ribociclib (RCB) via the topical route to …

Recent advancement of nanosponges in pharmaceutical formulation for drug delivery systems

V Mahalekshmi, N Balakrishnan… - Journal of Applied …, 2023 - japsonline.com
Through nanotechnology, nanosponges (NS) have a great impetus to develop ongoing
research in drug delivery systems. In several pharmaceutical preparations, concern about …

Novel indolyl 1, 2, 4-triazole derivatives as potential anti-proliferative agents: in silico studies, synthesis, and biological evaluation

SA Ghobish, KO Mohamed, N Farag… - RSC Medicinal …, 2024 - pubs.rsc.org
A new series of indolyl 1, 2, 4-triazole scaffolds was designed, synthesised, and biologically
evaluated for their inhibitory activity against both CDK4 and CDK6. The results ranged from …

Nanosponges–Road Less Explored Changing Drug Delivery Approach: An Explicative Review

S Nandi, D Karati, S Mukherjee - Current Pharmaceutical …, 2024 - ingentaconnect.com
Nanotechnology exhibits a wide range of applications in the domain of disease therapy,
diagnosis, biological detection, and environmental safeguards. The cross-linked polymeric …